Results 111 to 120 of about 178,987 (204)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Ionic Liquid Biospheres. [PDF]

Life (Basel)
Seager S, Bains W, Iakubivskyi I, Agrawal R, Jenkins J, Shinde P, Petkowski JJ.   +6 more
europepmc   +1 more source

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber, Sophie‐Charlotte Bartel, Michael Boch, Christoph Rosen, Michael Bodmer, Balthasar Luzius Hug, Thomas Stammschulte, Patrick E. Beeler   +7 more
wiley   +1 more source

Examining the Compositional Selectivity of Hydrocarbon Oxidation Products Using Liquid-Liquid Extraction and Solid-Phase Extraction Techniques. [PDF]

Environ Sci Technol
Zito P, Ghannam R, Harsha ML, Bekins BA, Podgorski DC.   +4 more
europepmc   +1 more source

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

Antibacterial consumption in public health facilities in Uganda: a trend analysis of national warehouse distribution data 2022-2024. [PDF]

JAC Antimicrob Resist
Nsubuga B, Chelimo VM, Kayemba A, Ampaire P, Nambatya W, Rajab K, Twemanye V, Akello H, Ddamba A, Kamabare M, Arinaitwe D, Kakooza F, Walwema R.   +12 more
europepmc   +1 more source

Prioritizing Feasible and Impactful Actions to Enable Secure AI Development and Use in Biology

Biotechnology and Bioengineering, EarlyView.
ABSTRACT As artificial intelligence continues to enhance biological innovation, the potential for misuse must be addressed to fully unlock the potential societal benefits. While significant work has been done to evaluate general‐purpose AI and specialized biological design tools (BDTs) for biothreat creation risks, actionable steps to mitigate the risk
Josh Dettman, Emily Lathrop, Aurelia Attal‐Juncqua, Matthew Nicotra, Allison Berke   +4 more
wiley   +1 more source

Does solo publication still make sense? : Single-authored publications have been essential to scientific progress but are now facing extinction. [PDF]

EMBO Rep
Rull V.
europepmc   +1 more source

Addressing Small Data Challenges in Biopharmaceutical Development and Manufacturing: A Mini Review of Multi‐Fidelity Techniques

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The growing demand for biopharmaceutical products reflects their effectiveness in medical treatments. However, developing new biopharmaceuticals remains a major bottleneck, often taking up to a decade before market approval. Machine learning (ML) models have the potential to accelerate this process, but their success depends on access to large
Mohammad Golzarijalal, Uwe Aickelin, Ellen Otte   +2 more
wiley   +1 more source

Immunocompromised Status Definition in Observational Studies Using Electronic Health Records: A Scoping Review and a Proposal for a Phenotype Identification Algorithm. [PDF]

Pharmacoepidemiol Drug Saf
Riera-Arnau J, Luxi N, Riefolo F, Solorzano M, Pazos I, Ballarín E, Svingel LS, Chiusaroli L, Martín-Merino E, Barbieri E, Lopez-Lasanta M, Mohammadi S, Rotta D, Pacurariu A, Cohet C, Sturkenboom M, Durán CE, SAFETY‐VAC study consortium.   +17 more
europepmc   +1 more source