Results 91 to 100 of about 2,201,586 (280)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Bio-copper nanoparticle-based superhydrophobic membranes for sustainable oil/water separation

Water Science and Technology
The effective separation of oil and water presents a significant global challenge due to the growing prevalence of industrial oily wastewater. In this investigation, a superhydrophobic (SP) coating based on bio-copper (Cu) was successfully created using ...
A. Beagan, C. Chen, M. E. Mohamed
doaj   +1 more source

Recent advances in synthesis and application of perovskite quantum dot based composites for photonics, electronics and sensors

Science and Technology of Advanced Materials, 2020
In recent years, halide perovskite quantum dots (HP-QDs) based composites have been widely developed and used in various applications owing to their unique photonic, electronic and mechanical properties, as well as high stability to water, oxygen, heat ...
Yaxin Wang, Guanglong Ding, Jing-Yu Mao, Ye Zhou, Su-Ting Han   +4 more
doaj   +1 more source

Smooth-filamental transition of active tracer fields stirred by chaotic advection

, 1999
The spatial distribution of interacting chemical fields is investigated in the non-diffusive limit. The evolution of fluid parcels is described by independent dynamical systems driven by chaotic advection.
A. Péntek, C. Jung, Cristóbal López, D. L. Turcotte, D. W. Waugh, E. R. Abraham, F. Városi, G. Metcalfe, H. Aref, I. M. Sokolov, I. R. Epstein, J. M. Ottino, L. Matthews, Peter H. Haynes, R. Reigada, S. Edouard, S. K. Scott, S. Wiggins, Y. Kuramoto, Z. Toroczkai, Zoltán Neufeld   +20 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Substituted silane-diol polymers have improved thermal stability [PDF]

, 1966
Organosilicon polymers were synthesized to produce improved physical and chemical properties, including high thermal stability. Of the polymers produced, poly/4, 4 prime-bisoxybi- phenylene/diphenylsilane, formed from bis/anilino/diphenylsilane and p, p ...
Byrd, J. D., Curry, J. E.
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Stability of Glass-ceramic Solidified Body of High Level Chloride Salts from Pyro-reprocessing of Spent Nuclear Fuels

Yuanzineng kexue jishu
In comparison with spent fuels from pressurized water reactors, spent fuels from fast breeder reactors contain much more transuranic elements and fission products, and hence are of much higher radioactivity.
CHANG Jiong, WANG Jiateng, LIU Xiao, LI Longfei, BAO Liangjin, LONG Haoqi, TAN Shengheng
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Extracting Value from Marine and Microbial Natural Product Artifacts and Chemical Reactivity

Marine Drugs
Natural products are and continue to be a remarkable resource, rich in structural diversity, and endowed with valuable chemical and biological properties that have advanced both science and society.
Mark S. Butler, Robert J. Capon
doaj   +1 more source