Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Chemical Stability of Diphenhydramine in "Magic Mouthwash" Stored at Room and Refrigerated Temperatures for 90-Days. [PDF]
Tubolino M +3 more
europepmc +1 more source
Review on Chemical Stability of Lead Halide Perovskite Solar Cells. [PDF]
Zhuang J, Wang J, Yan F.
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Chemical Stability and Leaching Behavior of ECO EPDM in Acidic Fuel Cell-like Conditions. [PDF]
Foltuț D, Șoșoi GI, Șerban VA.
europepmc +1 more source
A study on the chemical stability of cholesterol-lowering drugs in concomitant simple suspensions with magnesium oxide. [PDF]
Kato G +7 more
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Overcoming Challenges in Colloidal and Chemical Stability of Graphene Oxide with Exploration of Dispersing Solvent. [PDF]
Kim GW, Kim SY.
europepmc +1 more source
Correction to "Esterification of Lutein from Japanese Knotweed Waste Gives a Range of Lutein Diester Products with Unique Chemical Stability". [PDF]
Metličar V, Albreht A.
europepmc +1 more source

