Results 181 to 190 of about 1,800,080 (307)

Simulation strategies for microfabricated chemical systems

, 1998
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept.
Hsing, I-Ming, 1968-
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Towards more stable and ion-conductive organic electrolytes for rechargeable batteries

, 2019
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2019Cataloged from PDF version of thesis.Includes bibliographical references (pages 114-127).The global society urgently needs to remedy the effects of climate ...
Feng, Shuting,Ph.D.Massachusetts Institute of Technology.
core  

RETRACTED: Qadir et al. Synthesis and Characterization of Metal Particles Using Malic Acid-Derived Polyamides, Polyhydrazides, and Hydrazides. <i>Molecules</i> 2025, <i>30</i>, 134. [PDF]

Molecules
Qadir MF, Ameen S, Fatima R, Ullah N, Shazly GA, Bilal ASS, Nazar M, Sajjad A, Shah TA, Yang Y.   +9 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Correction: Lectin recognizing thermoresponsive double hydrophilic glycopolymer micelles by RAFT polymerization. [PDF]

RSC Adv
Sun K, Bligh SWA, Nie HL, Quan J, Zhu LM.   +4 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Correction: Proximity proteomics reveals OTUD6B regulation of stress granule dynamics through coalescence with VCP/p97. [PDF]

Cell Death Dis
Yang D, Liu Y, Hong Y, Miao E, Wang P, Sun Y, Zhou L, Liu S, Zhang Y, Qin H, Ye M, Liu H.   +11 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

A Reinforced Perfluorosulfonic Acid Membrane with PE Mesh. [PDF]

Membranes (Basel)
Dou Y, Su B, Jin Y, Zhang W, Wang Y, Wang Y.   +5 more
europepmc   +1 more source