Results 231 to 240 of about 15,527,582 (268)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

The Effect of Three Kinds of Surface Treatment Methods on the Corrosion and Wear Resistance of AM60B Magnesium Alloy with La, Ce Addition. [PDF]

Materials (Basel)
Wang S, Qiu Z, Huang N, Liang C, Jiang W.   +4 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

The Impact of SF3B1 Mutations on the Tumor Microenvironment and Response to Immunotherapy. [PDF]

Cancer Med
Cho KJ, Lim B.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Authentication of the Botanical Origins of Curcumae Radix Based on DNA Barcoding and HS-GC-IMS. [PDF]

Rapid Commun Mass Spectrom
Jiang Q, Yin J, Han X, Yong J, Sun R, Liu M, Wang W, Wang Y, Song M, Xiang B, Yu H.   +10 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

A Unified Classification of Waste Plastic Chemical Recycling: Pyrolysis, Gasification, Depolymerization, and Dissolution. [PDF]

ChemSusChem
Kim JS.
europepmc   +1 more source

Integrated Sugar-Acid-Phenolic Profiling Identifies Distinct Chemical Types Associated with Antioxidant Capacity in Apple Pulp Samples. [PDF]

Foods
Zheng H, Zhang H, Wang T, Peng T, Zhong L, Fu K, Cao Y, Zhang X, Tang L.   +8 more
europepmc   +1 more source