Results 71 to 80 of about 815,809 (265)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Dumping in the Global Dixie: Circle of Poison and the Contamination of the Global South
The 1981 publication of David Weir and Mark Shapiro’s exposé Circle of Poison almost ten years after the banning of DDT represented how the landscape of understandings about hazardous chemicals and their regulation had changed.
Amy M. Hay
doaj +1 more source
The EU countries have realised necessity of a legal regulation of the chemical substances for health protection of the person and maintenance of natural balance.
О. С. Бабенко
doaj +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Legal issues of improving environmental legislation in the field of chemical safety
Decisive steps to transform social relations are a complex process that requires thorough study and deep theoretical understanding of representatives of various scientific fields, including lawyers.
Askarova A.O., Suleimenova S.Zh.
doaj
Long-term analysis of drinking water quality in poultry and pig farms in Northwest Germany
Hygienically safe drinking water is essential for the health, well-being, and efficient production of livestock. In contrast to drinking water for human consumption, there are guidelines but no legal limits for drinking water for animals.
Pia Münster, Nicole Kemper
doaj +1 more source
As part of the EU-project COMICS, high throughput versions of the comet assay was developed. In order to test the performance of the new formats; the novel 12-gel slide and the 96-minigel film were compared with standard 3-gel slides for their ability to
Kristine Bjerve Gutzkow +6 more
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Chemical Contaminants Associated with Palm Wine from Nigeria Are Potential Food Safety Hazards
Recent analysis of palm wine, a traditional drink fermented mainly by yeasts, revealed the presence of several chemicals that were not products of yeast fermentation. The chemicals included styrene, benzene, trimethyldioxolane, dichloromethane, methylene
Ogueri Nwaiwu, Martin Itumoh
doaj +1 more source

