Results 141 to 150 of about 207,787 (293)
Emerging micropollutants (EMPs)—which include endocrine disruptors, pharmaceuticals, personal care products, pesticides, and industrial chemicals—have recently received global attention due to their detection in the environment at trace levels and being ...
Shifare Berhe Gebru +1 more
doaj +1 more source
Job Creation in the Manufacturing Revival [PDF]
[Excerpt] After rebounding from the 2007-2009 recession, U.S. manufacturing output has grown little since the second half of 2014. Over the same period, employment in the U.S. manufacturing sector has been flat. These trends defy expectations that forces
Levinson, Marc
core +2 more sources
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Insights into a long life without cancer: The case of the bowhead whale
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Nitrosamines: Emerging chemical contaminants of concern in pharmaceutical and biological systems
Nitrosamines are a class of compounds characterized by a nitroso group bonded to an amine (R₁N(-R₂)-N=O) and are commonly found in water, food, and pharmaceutical products. Their presence in drug substances has raised significant global concern due to their genotoxic and carcinogenic potential.
openaire +1 more source
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Reproductive health indicators of fishes from Pennsylvania watersheds: association with chemicals of emerging concern. [PDF]
Blazer VS +9 more
europepmc +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
TECHNICAL CHANGE AND NEW DIRECTIONS FOR COTTON PRODUCTION [PDF]
This report summarizes a year-long study of the current and future role of technology in the Mid-South, Southeast, and High Plains cotton production systems. Specific research objectives were to: 1) Identify the impacts of emerging technology on regional
Kazmierczak, Richard F., Jr. +1 more
core +1 more source

