Results 131 to 140 of about 3,861,697 (308)

Efficient Molecular Dynamics Simulations of Multiple Radical Center Systems Based on the Fragment Molecular Orbital Method [PDF]

open access: yes, 2014
The fully analytic energy gradient has been developed and implemented for the restricted open-shell Hartree–Fock (ROHF) method based on the fragment molecular orbital (FMO) theory for systems that have multiple open-shell molecules.
Nakamura, Shinichiro   +5 more
core  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Understanding Chemical Reactions in Secondary Education: Meta-Analysis Based on Conceptual Fields Theory and Meaningful Learning

open access: yesEducación Química
Understanding chemical reactions remains a central challenge in secondary chemistry education, requiring the integration of conceptual, representational, and procedural knowledge.
Fernando Fontalvo, Tarcilo Torres Valois
doaj   +1 more source

Evaluation of synthetic sphingolipid analogs as ligands for peroxisome proliferator-activated receptors

open access: yes, 2009
10.1016/j.bmcl.2009.02.004Bioorganic and Medicinal Chemistry Letters1961643 ...
Park, Jeong-Ju   +17 more
core   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Papers from the Department of Chemistry and Mineralogy ...

open access: yes, 1896
Reprinted from the American journal of science, the Transactions of the Royal Society of Canada, and other scientific serials.No. 1 title reads: Papers from the Department of Chemistry and Mineralogy; no.
McGill University. Dept. of Chemistry and Mineralogy.
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Environmental Analytical Chemistry

open access: yesMolecules
Environmental analytical chemistry has evolved into a well-established interdisciplinary field (analytical chemistry, pollution chemistry, chemical engineering, etc [...]
Stefan Tsakovski, Tony Venelinov
openaire   +3 more sources

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