Results 71 to 80 of about 3,861,697 (308)

The metamorphosis of analytical chemistry [PDF]

Analytical and Bioanalytical Chemistry, 2019
AbstractDefining analytical chemistry as the measurement of isolated compositional features in a selected study object ignores the unique perspective that analytical chemists bring to twenty-first century science and society. In this feature article, we will discuss some of the existing preconceptions and misinterpretations of analytical chemistry that
Adams, Freddy, Adriaens, Mieke
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

A Perspective Approach to Study the Valency-Based Irregular Indices for Benzenoid Planar Octahedron Structures

Journal of Chemistry, 2023
The molecular topology and the chemical structures which are not regular perform a dominant character in designing the compound in connection with their physical and chemical properties.
Maria Singaraj Rosary, Ammar Alsinai, Mohammad Kamran Siddiqui, Hanan Ahmed   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Distribution of Total and Organic Mercury in Superficial Soils in the Upper Manzanares River Watershed, Sucre State, Venezuela

Air, Soil and Water Research, 2008
Total and organic mercury contents were determined from samples of surface soils (0-5 cm), sieved at ≤63 μm. collected from 10 different locations in the upper Manzanares River watershed, using cold vapor atomic absorption spectroscopy. Methylmercury was
Yahsέ Rojas Challa, Luisa Rojas de Astudillo, Armando Ramirez, Andrέs Escalona, Gregorio Martínez   +4 more
doaj   +1 more source

Analytic calculations of anharmonic infrared and Raman vibrational spectra [PDF]

, 2016
Using a recently developed recursive scheme for the calculation of high-order geometric derivatives of frequency-dependent molecular properties [Ringholm et al., J. Comp.
Cornaton, Yann, Ringholm, Magnus, Louant, Orian, Ruud, Kenneth   +3 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Overview of novel nanobiosensors for electrochemical and optical diagnosis of leukemia: Challenge and opportunity

Journal of Innovative Optical Health Sciences
Leukemia is one of the ten types of cancer that causes the biggest death in the world. Compared to other types of cancer, leukemia has a low life expectancy, so an early diagnosis of the cancer is necessary.
Ulya Farahdina, Tahta Amrillah, Mashuri Mashuri, Vannajan Sanghiran Lee, Agus Rubiyanto, Nasori Nasori   +5 more
doaj   +1 more source

Species-specific lipophilicities of fluorinated diketones in complex equilibria systems and their potential as multifaceted reversible covalent warheads

Communications Chemistry, 2023
Combined molecular, physicochemical and chemical properties of electrophilic warheads can be applied to create covalent drugs with diverse facets. Here we study these properties in fluorinated diketones (FDKs) and their multicomponent equilibrium systems
Ishay Columbus, Lee Ghindes-Azaria, Ido Michael Herzog, Eliav Blum, Galit Parvari, Yoav Eichen, Yoram Cohen, Eytan Gershonov, Eyal Drug, Sigal Saphier, Shlomi Elias, Boris Smolkin, Yossi Zafrani   +12 more
doaj   +1 more source