Results 121 to 130 of about 3,192,458 (357)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Retracted: Electrochemical Application of Structured Color Nanotextile Materials in Garment Design

Journal of Chemistry, 2023
Journal of Chemistry
doaj   +1 more source

Correction: Design, synthesis, and anti-plasmodial profiling of oxalamide-linked 4-aminoquinoline-phthalimide hybrids. [PDF]

RSC Med Chem
Gupta N, Rani A, Kumar K, Raj R, Kumar V.   +4 more
europepmc   +1 more source

Spontaneous Mirror Symmetry Breaking in the Limited Enantioselective Autocatalysis Model: Abyssal Hydrothermal Vents as Scenario for the Emergence of Chirality in Prebiotic Chemistry [PDF]

, 2013
Josep M. Ribó, Joaquim Crusats, Zoubir El‐Hachemi, Albert Moyano, Celia Blanco, David Hochberg   +5 more
openalex   +1 more source

Archaeological Chemistry [PDF]

Accounts of Chemical Research, 1983
openaire   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Retracted: Application of Visual Communication Combined with Electrochemistry in Ceramic Carving Product Design

Journal of Chemistry, 2023
Journal of Chemistry
doaj   +1 more source

Correction: Room temperature sensing of CO₂ using <i>C</i>3-symmetry pyridinium-based porous ionic polymers with triazine or benzene cores. [PDF]

RSC Adv
Alshubramy MA, Alamry KA, Alorfi HS, Ismail SH, Rezki N, Aouad MR, Al-Sodies S, Hussein MA.   +7 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Retracted: Combination of Fruit and Vegetable Storage and Fresh-Keeping with Postharvest Heat Treatment

Journal of Chemistry
Journal of Chemistry
doaj   +1 more source