Results 121 to 130 of about 6,846,511 (358)

Black Hole Chemistry

, 2014
The mass of a black hole has traditionally been identified with its energy. We describe a new perspective on black hole thermodynamics, one that identifies the mass of a black hole with chemical enthalpy, and the cosmological constant as thermodynamic ...
Kubiznak, David, Mann, Robert B.
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Library Design in Combinatorial Chemistry by Monte Carlo Methods

, 2000
Strategies for searching the space of variables in combinatorial chemistry experiments are presented, and a random energy model of combinatorial chemistry experiments is introduced.
B. M. Cole, C. J. Geyer, D. E. Akporiaye, E. Danielson, E. Danielson, E. Marinari, E. Reddington, E. W. McFarland, F. M. Menger, G. Briceño, J. Wang, K. Burgess, L. D. Bogarad, M. B. Francis, M. C. Pirrung, M. Falcioni, Marco Falcioni, Michael W. Deem, P. Bratley, P. Cong, R. B. van Dover, S. I. Zones, T. A. Dickinson, T. Novet, W. H. Weinberg, X.-D. Xiang   +25 more
core   +1 more source

AspergillussectionNidulantes(formerlyEmericella): Polyphasic taxonomy, chemistry and biology

, 2016
A J Chen, Jens C. Frisvad, Bing‐Da Sun, János Varga, Sándor Kocsubé́, Jan Dijksterhuis, Daewoo Kim, S-B Hong, J. Houbraken, Robert A. Samson   +9 more
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Corrigendum to “Distribution and Bioaccumulation of Perfluoroalkyl Acids in Xiamen Coastal Waters”

Journal of Chemistry, 2022
Journal of Chemistry
doaj   +1 more source

Interactive Effect of Hysteresis and Surface Chemistry on Gated Silicon Nanowire Gas Sensors

, 2012
Yair Paska, Hossam Haick
openalex   +2 more sources

Entering the Chemistry World of Fermented Stinky Tofu [PDF]

, 2020
LI Xia-lei, Yongjie Lai, Xun Li
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source