Results 211 to 220 of about 4,421,535 (310)
The FunAqua dataset of global fungal biodiversity in aquatic ecosystems. [PDF]
Sci DataPrins V, Tedersoo L, Mikryukov V, Paiste P, Sepp M, Grossart H, Kisand V, Laas A, Tammert H, Abarenkov K, Agan A, Agasild H, Agha R, Alatalo J, Alvarez-Manjarrez J, Ameryk A, Anderson J, Anslan S, Antão-Geraldes A, Antosiak A, Funck JA, Arias-Real R, Ariyan M, Bahram M, Bansal S, Bao R, Beck S, Bernotas P, Berry N, Bertilsson S, Birnbaum C, Bonk M, Borges AV, Botez F, Brearley FQ, Brookes J, Bruno D, Budzyńska A, Bullerjahn G, Bundschuh M, Calheiros-Nogueira B, Calore R, Capelli C, Caputo L, Carballeira R, Chronis I, Čiampor F, Čiamporová-Zaťovičová Z, Craig D, Csabai Z, Cukrov N, da Silva L, de Eyto E, Delgado J, Dimante-Deimantovica I, Domaizon I, Dondajewska-Pielka R, Dornan T, Drenkhan R, Drouillard K, Duarte S, Dulya O, Dzhulai A, Dziga D, Egeter B, Espenberg M, Färkkilä S, Fazi S, Feckler A, Fenoy E, Fernandes I, Ferreira S, Ferreira V, Fleituch T, Fornaroli R, Freiwald A, Frenken T, Gaffney P, García-Oliva O, Geara H, Gkelis S, Gohar D, Gołdyn R, Grandjean F, Gsell A, Gutiérrez-Cánovas C, Haase P, Hagh-Doust N, Harris T, Hashem A, Havens S, Heidari B, Higgins S, Moghaddam MH, Ibrahim A, Jerinkić D, Jones S, Kagami M, Kahar S, Kangro K, Kariman K, Kataržytė M, Kepfer-Rojas S, Khan H, Knoll LB, Knorrn A, Kõljalg U, Konstantinou D, Kotta J, Kowalczewska-Madura K, Kozak A, Kulawig B, Kupagme J, Kušan I, Laarmaa R, Laas P, Langenheder S, Lanzén A, Lateef A, Ligi M, Löffler T, Lortou U, Lujza K, MacConnell T, Maček I, Macreadie P, Maileht K, Marazzi F, Marcello L, Markovskaja S, Martin A, Martínez S, Mata V, Matočec N, McKay R, McKindles K, Mehrshad M, Menéndez M, Merino N, Mešić A, Moctar S, Moza M, Nõges P, Nõges T, O'Hanlon R, Öğlü B, Oja J, Okello W, Orav-Kotta H, Orr P, Osemwegie I, Padisák J, Pajunen V, Panou M, Papatheodoulou A, Pavlovska M, Pearman J, Pehlak H, Peng X, Pereira A, Pereira R, Pernecker B, Picazo F, Pinnow S, Pochekutova P, Põlme S, Pontevedra-Pombal X, Pošta A, Prekrasna-Kviatkovska Y, Pruuli J, Pruuli M, Pruuli T, Radoja N, Rahimlou S, Rannap R, Rasconi S, Rasmussen A, Remmers W, Reyes L, Rhodes G, Roe C, Rojas-Castillo O, Roslin T, Runnel K, Rusch J, Rybak M, Rychtecký P, Sahadevan S, Saitta A, Salehi-Najafabadi A, Santi I, Sarapuu J, Schäfer RB, Schneeweiss A, Scholz B, Selmeczy G, Smederevac-Lalić M, Sommaruga R, Stetler J, Stoica E, Stoll S, Strand D, Tamm M, Tapolczai K, Tarand J, Teurlincx S, Thompson J, Thomson-Laing G, Tiirmann L, Tkalčec Z, Trbojević I, Trevathan-Tackett S, Tsiarta N, Tuvikene A, Tuvikene L, Vacaflores-Argandoña M, Vahter T, Vaino K, Val AL, Vandergoes M, Vasemägi A, Vask A, Vasquez M, Veríssimo J, Vesamäki J, Virta L, Visser P, Viza A, Vrålstad T, Ward CS, Waryszak P, Wierenga J, Wilson P, Wood S, Woźniczka A, Wurzbacher C, Zingel P, Znachor P, Dela Cruz TEE, Panksep K. +239 moreeuropepmc +1 more sourcePAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann +10 morewiley +1 more sourceSpatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours +11 morewiley +1 more sourceInhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli +10 morewiley +1 more source
