G-Quadruplex Dynamics Contribute To Regulation Of Mitochondrial Gene Expression [PDF]
, 2019 Single-stranded DNA or RNA sequences rich in guanine (G) can adopt non-canonical structures known as G-quadruplexes (G4). Mitochondrial DNA (mtDNA) sequences that are predicted to form G4 are enriched on the heavy-strand and have been associated with ...
Alder, J. K. +18 more
core +3 more sources
Effect Of Zinc Cations On The Kinetics Of Supramolecular Assembly And The Chirality Of Porphyrin J-Aggregates [PDF]
, 2017 Dilute aqueous solutions of anionic meso-4-sulfonatophenyl-porphyrin (TPPS) extract zinc(ii) ions from glass or quartz surfaces at room temperature and efficiently form the corresponding metal complex (ZnTPPS). The partial or complete formation of ZnTPPS
Castriciano, M. A. +5 more
core +3 more sources
Interactions Between Spermine-Derivatized Tentacle Porphyrins And The Human Telomeric DNA G-Quadruplex [PDF]
, 2018 G-rich DNA sequences have the potential to fold into non-canonical G-Quadruplex (GQ) structures implicated in aging and human diseases, notably cancers.
Chen, Jessica, , \u2717 +5 more
core +1 more source
Sinorhizobium Meliloti, A Bacterium Lacking The Autoinducer-2 (AI-2) Synthase, Responds To AI-2 Supplied By Other Bacteria [PDF]
, 2008 Many bacterial species respond to the quorum-sensing signal autoinducer-2 (AI-2) by regulating different niche-specific genes. Here, we show that Sinorhizobium meliloti, a plant symbiont lacking the gene for the AI-2 synthase, while not capable of ...
McAuley, J. R. +4 more
core +2 more sources
Structural Insights From HIV-Antibody Co-Evolution And Related Immunization Studies [PDF]
, 2018 Human immunodeficiency virus type 1 (HIV-1) is a rapidly evolving pathogen and causes the acquired immunodeficiency syndrome (AIDS) in humans. There are ~30-35 million people infected with HIV around the world, and ~25 million have died since the first ...
Fera, Daniela +4 more
core +1 more source
Synthesis And Characterization Of (pyNO−)2GaCl: A Redox-Active Gallium Complex [PDF]
, 2018 We report the synthesis of a gallium complex incorporating redox-active pyridyl nitroxide ligands. The (pyNO−)2GaCl complex was prepared in 85% yield via a salt metathesis route and was characterized by 1H and 13C NMR spectroscopies, X-ray diffraction ...
Carroll, P. J. +5 more
core +2 more sources
A Complex Stereochemical Relay Approach To The Antimalarial Alkaloid Ocimicide A1. Evidence For A Structural Revision [PDF]
, 2017 Ocimicide A1 (1) and the semisynthetic derivative ocimicide A2 (2) are highly potent antimalarial agents efficacious against chloroquine-sensitive and -resistant Plasmodium falciparum strains with IC50 values in the nanomolar and picomolar range ...
Herzon, S. B. +4 more
core +2 more sources
Rethinking the education of chemists - the odyssey is over, time for action! [PDF]
, 2003 Chemistry is a mature discipline with a distinguished pedigree and a long tradition, but times are changing and student numbers in chemistry are declining.
Wallace, RG
core +1 more source
The Chemistry of Alliums [PDF]
Molecules, 2018 Physiologically active sulfur-containing compounds produced by Allium spp. have long fascinated chemists, biochemists, and biologists.[...]
Martin Gruhlke, Alan Slusarenko
openaire +5 more sources