Results 81 to 90 of about 4,421,535 (310)

A consistent molecular hydrogen isotope chemistry scheme based on an independent bond approximation [PDF]

open access: yes, 2009
The isotopic composition of molecular hydrogen (H<sub>2</sub>) produced by photochemical oxidation of methane (CH<sub>4</sub>) and Volatile Organic Compounds (VOCs) is a key quantity in the global isotope budget of (H<sub>2 ...
Sub Atmospheric physics and chemistry   +8 more
core   +3 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

The Graduate Program in Chemistry & Biochemistry, circa 1995

open access: yes, 1995
Table of Contents: The University (p. 1) -- Austin (p. 3) -- The Department (p. 5) -- Mallet Chemistry Library (p. 6) -- Mass Spectrometry Facility (p. 7) -- Nuclear Magnetic Resonance Laboratory (p. 8) -- X-Ray Diffraction Laboratory (p.
Chemistry Department
core   +1 more source

The Chemistry of Anesthetics [PDF]

open access: yesScience, 1911
IDIOSYNCRASY has in the past accounted for-serves now to account for-unusual observations in the use of drugs, and perhaps will continue to cover much of our lack of information as to their real therapeutic action, but I am of the opinion that it is a "magic skin." Sacred, profane and mythological literature abound in incident, fact and fancy, showing ...
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The University of Texas at Austin, Department of Chemistry and Biochemistry, Graduate Studies, circa 2006

open access: yes, 2006
Table of Contents: Letter from the Chairman (p. 1) -- Austin (p. 2) -- The University of Texas (p. 3) -- Chemistry and Biochemistry (p. 4) -- Research Centers (p. 5) -- Graduate Program (p. 6) -- Research Areas (p. 8) -- Faculty (p. 10) -- Admissions (p.
Chemistry Department
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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