Results 121 to 130 of about 168,140 (338)

Surgical Procedure of Lateral Lymph Node Dissection for Advanced Lower Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
Lateral lymph node dissection (LLND) is an effective surgical approach for lower rectal cancer. This paper outlines key points from the Japan Society of Gastroenterological Surgery consensus meeting, including standardized LLND techniques and procedural highlights.
Mamoru Uemura, Jun Watanabe, Akio Shiomi, Takashi Akiyoshi, George J. Chang, Yukihide Kanemitsu, Ichiro Takemasa, Yoshiharu Sakai, Masahiko Watanabe, Itaru Endo   +9 more
wiley   +1 more source

Stereotactic MRI-guided Adaptive Radiation Therapy (SMART) for Locally Advanced Pancreatic Cancer: A Promising Approach. [PDF]

, 2018
Locally advanced pancreatic cancer (LAPC) is characterized by poor prognosis and low response durability with standard-of-care chemotherapy or chemoradiotherapy treatment.
Cao, Minsong, Lamb, James, Lee, Percy, Low, Daniel A, Luterstein, Elaine, Raldow, Ann C, Steinberg, Michael L   +6 more
core   +1 more source

Association Between the Degree of Arterial Contact Angle and Survival in Patients With Borderline Resectable Pancreatic Cancer

Annals of Gastroenterological Surgery, EarlyView.
This study evaluated the prognostic impact of arterial contact angle in patients with borderline resectable pancreatic cancer undergoing neoadjuvant therapy and surgery. An arterial contact angle of ≥ 90° was associated with higher R1 resection rates and worse survival outcomes.
Katsuhisa Ohgi, Ryo Ashida, Mihoko Yamada, Shimpei Otsuka, Yoshiyasu Kato, Rui Sato, Akifumi Notsu, Katsuhiko Uesaka, Teiichi Sugiura   +8 more
wiley   +1 more source

A Catalase-Like Metal-Organic Framework Nanohybrid for O2 -Evolving Synergistic Chemoradiotherapy.

Angewandte Chemie, 2019
Tumor hypoxia, the "Achilles' heel" of current cancer therapies, is indispensable to drug resistance and poor therapeutic outcomes especially for radiotherapy.
Zhimei He, Xiaolin Huang, Chen Wang, Xiangli Li, Yijing Liu, Zijian Zhou, Sheng Wang, Fuwu Zhang, Zhantong Wang, Orit Jacobson, Jun‐Jie Zhu, Guocan Yu, Yunlu Dai, Xiaoyuan Chen   +13 more
semanticscholar   +1 more source

Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: A review of the National Cancer Database [PDF]

, 2017
For elderly patients with locally advanced esophageal cancer, therapeutic approaches and outcomes in a modern cohort are not well characterized. Patients ≥70 years old with clinical stage II and III esophageal cancer diagnosed between 1998 and 2012 were ...
Bradley, Jeffrey D, Kozower, Benjamin, Lockhart, A. Craig, Meyers, Bryan F, Parikh, Parag J, Perkins, Stephanie M, Puri, Varun, Roach, Michael C, Robinson, Cliff G, Samson, Pamela P, Vlacich, Gregory   +10 more
core   +2 more sources

Brassinin from Brassica campestris L. inhibits colorectal cancer by inducing p62/NRF2/GPX4‐regulated ferroptosis

Animal Models and Experimental Medicine, EarlyView.
BSN suppresses the cell viability of colorectal cancer by inducing GPX4‐regulated ferroptosis. BSN may bind to NRF2 protein to inactivate the NRF2 signaling, inhibiting the expression of p62 and HO‐1. Abstract Background Indole phytoalexins, plant‐derived compounds present in cruciferous vegetables, have demonstrated anticancer properties.
Shi‐Yuan Wen, Rui‐Rui Gao, Yan‐Yan Chen, Yi‐Jie Wang, Xin‐Tong Wang, Hai‐Xin Liu   +5 more
wiley   +1 more source

A novel sphingolipid metabolism-related long noncoding RNA signature predicts the prognosis, immune landscape and therapeutic response in pancreatic adenocarcinoma

Heliyon
Sphingolipid metabolism affects prognosis and resistance to immunotherapy in patients with cancer and is an emerging target in cancer therapy with promising diagnostic and prognostic value.
Xiaolan He, Zhengyang Xu, Ruiping Ren, Peng Wan, Yu Zhang, Liangliang Wang, Ying Han   +6 more
doaj  

Uptake of systematic reviews and meta-analyses based on individual participant data in clinical practice guidelines: descriptive study. [PDF]

, 2015
To establish the extent to which systematic reviews and meta-analyses of individual participant data (IPD) are being used to inform the recommendations included in published clinical ...
Cochrane IPD Meta-analysis Methods Group, ., Emberson, JR, Gueyffier, F, Rovers, MM, Rydzewska, LH, Stewart, LA, Vale, CL   +6 more
core   +2 more sources

Implementation of mass pharmacogenetic testing: Dihydropyrimidine dehydrogenase testing prior to fluoropyrimidine treatment for patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Pharmacogenomics enables personalization of drug therapy improving effectiveness and/or safety. Dihydropyrimidine dehydrogenase [DPYD] testing prior to fluoropyrimidine chemotherapy was commissioned by NHS England in response to an update from the Medicines and Healthcare products Regulatory Agency.
Nisha Shaunak, Jessica Keen, Anna Kim, Munir Pirmohamed, William G. Newman, Paul J. Ross   +5 more
wiley   +1 more source

Clinical significance of VEGF-A, -C and -D expression in esophageal malignancies [PDF]

, 2005
Vascular endothelial growth factors ( VEGF)- A, - C and - D are members of the proangiogenic VEGF family of glycoproteins. VEGF-A is known to be the most important angiogenic factor under physiological and pathological conditions, while VEGF-C and VEGF-D
Ahn MJ, Baatar D, Banks RE, Berse B, Boucher Y, Coia LR, Dirix LY, Du JR, Gu ZP, Guo WZ, Hefler L, Hickey K, Hironaka S, Isaka N, Ishikawa M, Karpanen T, Kato H, Kitadai Y, Kitamura K, Koide N, Koukourakis MI, Kukk E, Kumar H, Lackey VL, Lewis CE, Li Z, Maniwa Y, Millikan KW, Mobius C, Nagata J, Nguyen M, Noguchi T, Nor JE, Ohtsu A, Roberts WG, Rockwell S, Roder JD, Salven P, Shih CH, Spence GM, Suit HD, Theunissen PH, Uchida S, Vogel SB, Wallner G, Weingartner K, Yamamoto Y, Yang B, Yeo KT   +48 more
core   +1 more source