Results 121 to 130 of about 97,795 (300)
Objectives: Thymic carcinoma (TC) is rare. There is no evidence regarding the treatment strategies for unresectable locally advanced thymic carcinomas. Definitive chemoradiotherapy may treat this condition. However, an appropriate concurrent chemotherapy
Koichiro Nozaki +4 more
doaj +1 more source
Approximately 30% of locally advanced rectal cancer patients might not benefit from chemoradiotherapy; however, the response to neoadjuvant chemoradiotherapy in these cases is difficult to predict. Pim-3 is a member of the provirus integration site for a
Xiao-jun Wu +7 more
core +1 more source
Lymphoedema in Head and Neck Cancer Survivors: Healthcare Professionals' Perspectives
ABSTRACT Introduction Improvements in head and neck cancer (HNC) treatment have increased survival rates, resulting in survivors living with side effects, such as head and neck lymphoedema (HNL). We aimed to document healthcare professionals' perceptions of HNL, approaches to managing HNL, and integration of HNL management into routine practice in ...
Kadriye Yusra Sert +6 more
wiley +1 more source
ABSTRACT Background In T1–T2 oropharyngeal squamous cell carcinoma (OPSCC), factors associated with patient‐reported quality of life after transoral robotic surgery (TORS) are poorly defined. Methods Retrospective cohort of 59 patients with T1–T2 OPSCC treated with TORS.
Paolo Tesauro +5 more
wiley +1 more source
Activated dormant stem cells recover spermatogenesis in chemoradiotherapy-induced infertility
Summary: Male infertility is a recognized side effect of chemoradiotherapy. Extant spermatogonial stem cells (SSCs) may act as originators for any subsequent recovery.
Shu-Hua Yang +7 more
core +1 more source
ABSTRACT Background Patients with head and neck cancer (HNC) are at risk of impaired muscle health due to metabolic disturbances, reduced nutritional intake, and treatment‐related toxicities. Because muscle health supports physical capacity and independence, its decline may affect quality of life (QoL).
Tycho Zuijlen +4 more
wiley +1 more source
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto +21 more
wiley +1 more source
Nutritional and clinical outcomes of chemoradiotherapy for clinical T1N0M0 esophageal carcinoma
Katsuyuki Sakanaka,1 Kota Fujii,1 Yuichi Ishida,1 Shin’ichi Miyamoto,2 Takahiro Horimatsu,3 Manabu Muto,3 Takashi Mizowaki11Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, Japan ...
Sakanaka K +6 more
doaj
ABSTRACT Adjuvant nivolumab is approved for esophageal or gastroesophageal junction cancer after neoadjuvant chemoradiotherapy and resection. In the CheckMate‐577 trial, Grade 3–5 nivolumab‐related adverse events (AEs) occurred in 5% of patients, with early discontinuation due to toxicity in 9%. However, real‐world data on immunotherapy‐related adverse
Michelle Koops van ’t Jagt +7 more
wiley +1 more source
Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer
ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue +6 more
wiley +1 more source

