Results 121 to 130 of about 97,795 (300)

Definitive chemoradiotherapy with Carboplatin Plus Paclitaxel for Unresectable Locally Advanced Thymic Carcinoma: A case series

open access: yesCurrent Problems in Cancer: Case Reports
Objectives: Thymic carcinoma (TC) is rare. There is no evidence regarding the treatment strategies for unresectable locally advanced thymic carcinomas. Definitive chemoradiotherapy may treat this condition. However, an appropriate concurrent chemotherapy
Koichiro Nozaki   +4 more
doaj   +1 more source

Pim-3 as a potential predictor of chemoradiotherapy resistance in locally advanced rectal cancer patients

open access: yes, 2017
Approximately 30% of locally advanced rectal cancer patients might not benefit from chemoradiotherapy; however, the response to neoadjuvant chemoradiotherapy in these cases is difficult to predict. Pim-3 is a member of the provirus integration site for a
Xiao-jun Wu   +7 more
core   +1 more source

Lymphoedema in Head and Neck Cancer Survivors: Healthcare Professionals' Perspectives

open access: yesHead &Neck, EarlyView.
ABSTRACT Introduction Improvements in head and neck cancer (HNC) treatment have increased survival rates, resulting in survivors living with side effects, such as head and neck lymphoedema (HNL). We aimed to document healthcare professionals' perceptions of HNL, approaches to managing HNL, and integration of HNL management into routine practice in ...
Kadriye Yusra Sert   +6 more
wiley   +1 more source

Association of HPV Status With Quality of Life After Transoral Robotic Surgery for T1–T2 Oropharyngeal Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background In T1–T2 oropharyngeal squamous cell carcinoma (OPSCC), factors associated with patient‐reported quality of life after transoral robotic surgery (TORS) are poorly defined. Methods Retrospective cohort of 59 patients with T1–T2 OPSCC treated with TORS.
Paolo Tesauro   +5 more
wiley   +1 more source

Activated dormant stem cells recover spermatogenesis in chemoradiotherapy-induced infertility

open access: yes
Summary: Male infertility is a recognized side effect of chemoradiotherapy. Extant spermatogonial stem cells (SSCs) may act as originators for any subsequent recovery.
Shu-Hua Yang   +7 more
core   +1 more source

The Association Between Muscle Health and Quality of Life in Patients With Head and Neck Cancer: A Systematic Review

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Patients with head and neck cancer (HNC) are at risk of impaired muscle health due to metabolic disturbances, reduced nutritional intake, and treatment‐related toxicities. Because muscle health supports physical capacity and independence, its decline may affect quality of life (QoL).
Tycho Zuijlen   +4 more
wiley   +1 more source

Sizing and concentration analysis of cfDNA using Biabooster technology: Results from a prospective plasma‐based collection of 77 patients with locally advanced unresectable esophageal cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto   +21 more
wiley   +1 more source

Nutritional and clinical outcomes of chemoradiotherapy for clinical T1N0M0 esophageal carcinoma

open access: yesCancer Management and Research, 2019
Katsuyuki Sakanaka,1 Kota Fujii,1 Yuichi Ishida,1 Shin’ichi Miyamoto,2 Takahiro Horimatsu,3 Manabu Muto,3 Takashi Mizowaki11Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, Japan ...
Sakanaka K   +6 more
doaj  

Tolerability of Adjuvant Nivolumab in Esophageal or Gastroesophageal Junction Cancer: A Real‐World Study

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Adjuvant nivolumab is approved for esophageal or gastroesophageal junction cancer after neoadjuvant chemoradiotherapy and resection. In the CheckMate‐577 trial, Grade 3–5 nivolumab‐related adverse events (AEs) occurred in 5% of patients, with early discontinuation due to toxicity in 9%. However, real‐world data on immunotherapy‐related adverse
Michelle Koops van ’t Jagt   +7 more
wiley   +1 more source

Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue   +6 more
wiley   +1 more source

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