Results 251 to 260 of about 93,945 (299)

Rationale for chemoradiotherapy

International Journal of Clinical Oncology, 2004
The rationale for combining chemotherapy (CT) and radiotherapy (RT) is based mainly on two ideas, one being spatial cooperation and the other the enhancement of radiation effects. Spatial cooperation is effective if CT is sufficiently active to eradicate subclinical metastases and if the primary local tumor is effectively treated by RT. In this regard,
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Pancreatic cancer chemoradiotherapy

Best Practice & Research Clinical Gastroenterology, 2016
Pancreatic cancer is the most lethal gastrointestinal tumour. Chemotherapy is the mainstay of therapy in the majority of the patients whereas resection is the only chance of cure but only possible in 15-20% of all patients. The integration of radiotherapy into multimodal treatment concepts is heavily investigated.
Brunner, Thomas, Seufferlein, Thomas
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Prodrugs in Genetic Chemoradiotherapy

Current Pharmaceutical Design, 2003
Improvements in the radiotherapeutic management of solid tumors through the concurrent use of gene therapy is a realistic possibility. Of the broad array of candidate genes that have been evaluated, those encoding prodrug-activating enzymes are particularly appealing since they directly complement ongoing clinical chemoradiation regimes.
Adam V, Patterson, Mark P, Saunders, Olga, Greco   +2 more
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Chemoradiotherapy for gastrointestinal cancers

Current Oncology Reports, 2005
New combinations of chemotherapy with radiotherapy for gastrointestinal cancers are showing evidence that improved outcomes may result from toxicity profiles associated with "targeted" systemic radiosensitizing agents. These new agents are also clinically attractive owing to such factors as oral bioavailability and patient dosing schedules, making them
Tyvin A, Rich, Christopher, Crane, Joshua D, Lawson, Jerome, Landry   +3 more
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Chemoradiotherapy for cervical cancer

European Journal of Cancer, 2002
Cervical cancer remains a major health problem worldwide, despite advances in screening. For patients with locally advanced stage disease, failure to obtain local-regional control usually results in death. In an effort to improve local-regional tumour control, neoadjuvant and concurrent chemoradiation has been tested.
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Timing and sequencing of chemoradiotherapy

1995
There are three main objectives in the treatment of cancer: (1) curing disease, (2) keeping the morbidity of treatment to a minimum, and (3) preserving function and cosmesis. It may be difficult to achieve all three of these objectives in all cases. However, cure may be the most important single goal.
D J, Haraf, R R, Weichselbaum, E E, Vokes   +2 more
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Chemoradiotherapy for lung cancer

Expert Opinion on Pharmacotherapy, 2005
Chemoradiotherapy is a standard treatment for both unresectable locally advanced non-small cell lung cancer and limited-stage small cell lung cancer. Cisplatin-based chemotherapy with concurrent thoracic radiotherapy yields a 5-year survival rate of approximately 15% for patients with unresectable locally advanced non-small cell lung cancer.
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Chemotherapy and chemoradiotherapy for esophageal cancer

Critical Reviews in Oncology/Hematology, 1998
Carcinoma of the esophagus is a highly virulent disease. Although surgery has generally been considered the standard therapy for local regionally confined esophageal cancer, the results remained poor with 5year survivals of 6–24% in Western countries [1]. In the results of a Japanese nationwide registration, the overall 5-year survival rate of resected
A, Ohtsu, S, Yoshida
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Radiotherapy and Chemoradiotherapy

2018
Neoadjuvant radiation therapy or chemoradiotherapy followed by surgery has the potential to improve patient survival by reducing the risk of locoregional and distant metastasis of gastric cardiac cancer in both thoracic and abdominal organs. Because of the limited case number in prior clinical trials on the efficacy of radiation or chemoradiotherapy ...
Xingchu Ni, Kun Huang
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Chemoradiotherapy in the treatment of rectal cancer

Hematology/Oncology Clinics of North America, 2002
The integration of radiotherapy to the adjuvant treatment of rectal cancer was prompted by the predominance of locoregional failures after curative surgery. This characteristic in the pattern of failure is one of the main reasons adjuvant radiotherapy plays a greater role in rectal cancer than in colon cancer.
Roberto J, Santiago, James M, Metz, Stephen, Hanh   +2 more
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