Results 81 to 90 of about 35,587 (239)

Olanzapine enhances the effect of conventional drugs in chemotherapy induced nausea and vomiting: A randomized clinical trial

Caspian Journal of Internal Medicine, 2022
Background: Chemotherapy inducing nausea and vomiting (CINV) is one of the significant   side  effects of anti-cancer treatment, and its full prevention is a potential challenge.
Atefe Khani, Ali Eishy Oskuyi, Rahim Asghari, Hamid Reza Khalkhali, Hamdollah Sharifi   +4 more
doaj  

Effect of Ginger Intake on Chemotherapy- Induced Nausea and Vomiting among Patients with Bladder Cancer [PDF]

Egyptian Journal of Health Care
Background: Chemotherapy-induced nausea and vomiting (CINV) is constitutes a major challange for patients with bladder cancer, frequently inadequately controlled by standared antiematic, ginger has historically been explored as an adjunctive therapy to ...
Sarah Mahmoud Ahmed Boriqa, Ahmed Abd El-Shafy, Raghda Yahia Abu El-Ela, Salwa Attia Mohamed Ahmed   +3 more
doaj   +1 more source

A phase IIa study of the anti‐PD‐L1 antibody avelumab in relapsed/refractory PTCL: The AVAIL‐T trial

British Journal of Haematology, EarlyView.
The AVAIL‐T study, the first evaluation of programmed death ligand 1 (PD‐L1) blockade in relapsed/refractory peripheral T‐cell lymphomas (PTCL), demonstrated limited single agent activity with durable responses seen in a minority. Circulating tumour DNA revealed distinct mutational dynamics and mass cytometry identified perturbed T‐cell subsets ...
Matthew J. Ahearne, Matthew A. Timmins, Charlotte Gaskell, Aimee Jackson, Clare Morland, Sonia Fox, Louise Hopkins, Nadia Nawaz, Susann Lehmann, Marc Wadsley, Caroline Cowley, Jacqueline Shaw, Naeem Khan, Nagesh Kalakonda, Christopher Trethewey, Ram Malladi, Paul Fields, Dima El Sharkawi, Michael Quinn, Nimish Shah, Andrew Davies, Kim Linton, Pam McKay, Rod Johnson, Simon D. Wagner, David Lewis, Graham P. Collins, Christopher P. Fox, Kate Cwynarski   +28 more
wiley   +1 more source

Ice massage on chemotherapy induced nausea and vomiting

مجله دانشگاه علوم پزشکی بیرجند, 2012
Background and Aim: Nausea and vomiting are the most common side effects of chemotherapy. The aim of the current study was to assess the effect of ice massage applied to the pericardium 6 (P6 or Neigaun) acupuncture point on nausea– vomiting due to
Mehdi Sadeghi Shermeh, Abbas Ebadi, Masoud Sirati Nir, Marzieh Azadian   +3 more
doaj  

Effect of Peppermint Inhalation on Chemotherapy Induced-Nausea and Vomiting in Children with Leukemia [PDF]

Alexandria Scientific Nursing Journal
Background: Today, leukemia is one of the most important health challenges in the world. Despite the many advances in malignancy treatment, children undergoing chemotherapy are still suffering from deliberating side effects. So, pediatric oncology nurses
Eman Arafa Badr, Hawaa Mohamed Hassan, Youssr Abd-Elsalam Gaafer, Maha Youssef Kamal   +3 more
doaj   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

Pronounced Reductions in Plasma Citrulline Indicate Severe Intestinal Mucosal Barrier Injury During Induction Therapy for Pediatric Acute Myeloid Leukemia

European Journal of Haematology, EarlyView.
ABSTRACT Objectives Pediatric acute myeloid leukemia (AML) chemotherapy regimens are frequently burdened by fever episodes, systemic inflammation and bloodstream infections (BSI). Mucosal barrier injury may contribute to these complications, but its role in childhood AML remains uninvestigated.
Carla Warley Kjær, Maria Ebbesen Sørum, Silvia De Pietri, Claus Moser, Malene Johanne Petersen, Marianne Hoffmann, Henrik Hasle, Sarah Weischendorff, Klaus Müller   +8 more
wiley   +1 more source

Chemotherapy-related nausea and vomiting - past reflections, present practice and future management

, 2004
Although much progress has occurred in the last decade regarding the management of chemotherapy-induced nausea and vomiting, these remain among the most intolerable side-effects of treatment and patients continue to report the negative impact such ...
M. MILLER, Miller, Morven, Kearney, Nora, N. KEARNEY   +3 more
core   +1 more source

Comparison of intestinal histopathological changes following teclistamab, BCMA‐directed CAR T, CD19‐directed CAR T and rituximab therapies

Histopathology, EarlyView.
This is a retrospective review of intestinal tract biopsies from patients treated with various cellular immunotherapies (BCMA and CD19‐directed CAR T, teclistamab and rituximab therapies). We found distinct but overlapping histologic patterns across treatment groups, with lamina propria plasma cell depletion, crypt apoptotic bodies and active ...
Olivia J Leung, Esther Baranov, Isairis Peralta Valerio, Robin Collingwood, Natalie Respond, Don Siegel, Pooja Devi, Kristen M. Stashek   +7 more
wiley   +1 more source