Results 81 to 90 of about 126,533 (310)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Organización bancaria colombiana Vol. 29 Num. 77.

open access: yesEstudios de Derecho, 1970
Organización bancaria colombiana. Segunda parte.
Enrique Trujillo Palacio
doaj  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

الصك (Cheque) واستخدامه في الدولة العربية الإسلامية

open access: yesمجلة الآداب, 2021
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بهجت كامل عبد اللطيف
doaj  

Você me daria um "cheque em branco"?

open access: yesRevista de Arqueologia, 2014
O presente artigo visa discutir o endosso institucional para acervos arqueológicos. Nesse caminho, aborda: a noção de endosso institucional, observando os princípios que regem essa ação e conceitos associados, com a finalidade de chamar a atenção para ...
Carlos Alberto Santos Costa   +1 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Acerca de la función de las escalas penales, las consecuencias de una contradicción normativa y la responsabilidad en virtud de la actio illicita in causa

open access: yesRevista Discusiones, 2010
En este trabajo, en primer lugar, analizo la sección donde Juan Pablo Alonso descarta que la respuesta al conflicto normativo pueda encontrarse en las escalas penales previstas para cada delito y sostengo lo contrario.
José Milton Peralta
doaj   +1 more source

Scots law and the UK codification of bills of exchange [PDF]

open access: yes, 2014
No abstract ...
Anderson, Ross Gilbert
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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