Results 11 to 20 of about 2,730 (156)

Small interfering RNA: Discovery, pharmacology and clinical development—An introductory review

British Journal of Pharmacology, Volume 180, Issue 21, Page 2697-2720, November 2023., 2023
Abstract Post‐transcriptional gene silencing targets and degrades mRNA transcripts, silencing the expression of specific genes. RNA interference technology, using synthetic structurally well‐defined short double‐stranded RNA (small interfering RNA [siRNA]), has advanced rapidly in recent years.
Priyanga Ranasinghe, Melisande L. Addison, James W. Dear, David J. Webb   +3 more
wiley   +1 more source

CatMass: software for calculating optimal sample masses for X‐ray absorption spectroscopy experiments involving complex sample compositions

Journal of Synchrotron Radiation, Volume 30, Issue 5, Page 1023-1029, September 2023., 2023
CatMass is a new software for calculating the optimal sample mass of samples with complex compositions (e.g. a supported metal catalyst mixed with a diluent) for X‐ray absorption and X‐ray scattering experiments with supplemental results to guide experimental design and collection geometry.This paper presents software for calculating the optimal mass ...
Jorge E. Perez-Aguilar, Ash Caine, Simon R. Bare, Adam S. Hoffman   +3 more
wiley   +1 more source

Pushing the Boundaries of Structural Heterogeneity with the Lipid A of Marine Bacteria Cellulophaga

ChemBioChem, Volume 24, Issue 10, May 16, 2023., 2023
Lipopolysaccharide and its lipid A from marine bacteria are a chemical gold for the development of new adjuvants and immune therapeutics. Here we defined the structure of three marine Cellulophaga species and the TLR4 activation potential of their lipopolysaccharide.
Roberta Cirella, Chiara Pagliuca, Molly Dorothy Pither, Elena Scaglione, Olga I. Nedashkovskaya, Oleg V. Chernikov, Kuo‐Feng Hua, Roberta Colicchio, Mariateresa Vitiello, Maxim S. Kokoulin, Alba Silipo, Paola Salvatore, Antonio Molinaro, Flaviana Di Lorenzo   +13 more
wiley   +1 more source

Nanoparticles for vaccine and gene therapy: Overcoming the barriers to nucleic acid delivery

WIREs Nanomedicine and Nanobiotechnology, Volume 14, Issue 6, November/December 2022., 2022
There is significant potential to improve the delivery of nucleic acid theraputics by engineering smart, responsive and targeted nanoparticle delivery systems. Abstract Nucleic acid therapeutics can be used to control virtually every aspect of cell behavior and therefore have significant potential to treat genetic disorders, infectious diseases, and ...
Lara M. Mollé, Cameron H. Smyth, Daniel Yuen, Angus P. R. Johnston   +3 more
wiley   +1 more source

Nonlinearity effects in the kicked oscillator [PDF]

, 2002
The quantum kicked oscillator is known to display a remarkable richness of dynamical behaviour, from ballistic spreading to dynamical localization. Here we investigate the effects of a Gross Pitaevskii nonlinearity on quantum motion, and provide evidence
A.A. Chernikov, A.A. Chernikov, A.B. Rechester, A.D. Bandrauk, A.D. Bandrauk, A.J. Lichtenberg, B.V. Chirikov, D. Shepelyansky, D.A. Steck, D.L. Shepelyansky, D.L. Shepelyansky, E. Ott, F. Benvenuto, F. Borgonovi, F. Dalfovo, F.M. Izrailev, F.M. Izrailev, G. Park, G.M. Zaslavsky, G.P. Berman, I. Dana, Laura Rebuzzini, R. Artuso, R. Artuso, R. Baer, Roberto Artuso, S.A. Gardiner, S.A. Gardiner, T.M. Fromhold, W.K. Hensinger   +29 more
core   +1 more source

Wiggler radiation at a low‐emittance storage ring and its usage for X‐ray absorption spectroscopy

Journal of Synchrotron Radiation, Volume 29, Issue 2, Page 462-469, March 2022., 2022
Experimental and computational studies of wigglers on low‐emittance storage rings are reported. EXAFS spectra for possible distortions originating from the source imperfection are also examined. It is concluded that wigglers are still an appropriate class of insertion devices, also on low‐emittance synchrotrons.A wiggler is a high‐power insertion ...
Konstantin Klementiev, Hamed Tarawneh, Pedro Fernandes Tavares   +2 more
wiley   +1 more source

Theories without the tree property of the second kind [PDF]

, 2012
We initiate a systematic study of the class of theories without the tree property of the second kind - NTP2. Most importantly, we show: the burden is "sub-multiplicative" in arbitrary theories (in particular, if a theory has TP2 then there is a formula ...
Chernikov, Artem
core   +3 more sources

Conformal Symmetry and Unification

, 1998
The Weyl-Weinberg-Salam model is presented. It is based on the local conformal gauge symmetry. The model identifies the Higgs scalar field in SM with the Penrose-Chernikov-Tagirov scalar field of the conformal theory of gravity.
Pawlowski, Marek
core   +1 more source

Dispersion‐compensated Rowland spectrometer: implications for uranium VB‐RIXS

Journal of Synchrotron Radiation, Volume 33, Issue 1, Page 218-226, January 2026.
A valence‐band resonant inelastic X‐ray scattering instrument, operating in the tender X‐ray range, uses an incoming beam with a linear energy dispersion to reach the intrinsic resolution of the Rowland spectrometer. Such a scheme is insensitive to the incident bandwidth and therefore preserves count‐rates despite the higher resolution.The total energy
Martin Sundermann, Manuel Harder, Ayman H. Said, Bernhard Keimer, Hlynur Gretarsson   +4 more
wiley   +1 more source

Invariant types in NIP theories

, 2015
We study invariant types in NIP theories. Amongst other things: we prove a definable version of the (p,q)-theorem in theories of small or medium directionality; we construct a canonical retraction from the space of M-invariant types to that of M-finitely
Simon, Pierre
core   +3 more sources