Results 151 to 160 of about 2,687,367 (305)

Health disparities in chronic liver disease

Hepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew   +3 more
wiley   +1 more source

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

British Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort, Marella C. E. van Ruissen, Lisanne C. A. Smidt, Naomi B. Klarenbeek, Philip H. K. Kremer, Manon A. A. Jansen, Jacobus Burggraaf, Joop M. A. van Gerven, Matthijs Moerland   +8 more
wiley   +1 more source

Fostamatinib and the risk of acute aortic dissection in immune thrombocytopenia

British Journal of Clinical Pharmacology, EarlyView.
Immune thrombocytopenia (ITP) is a rare autoimmune disorder characterized by platelet destruction. While most patients respond to first‐ or second‐line therapies, a small subset is multirefractory. Fostamatinib, an oral spleen tyrosine kinase (SYK) inhibitor, is a therapeutic option in these cases.
Paul Dalmas, Alexis Theron, Rita Badaoui, Stéphane Zaffran, Rayid Mchinda, Joelle Micallef, Nicolas Schleinitz, Mikael Ebbo   +7 more
wiley   +1 more source

Prediction of major adverse cardiovascular events following ST-segment elevation myocardial infarction using cardiac obesity marker—epicardial adipose tissue mass index: a prospective cohort study

Frontiers in Cardiovascular Medicine
BackgroundAlthough reperfusion therapy has led to improvements in the acute phase of ST-segment elevation myocardial infarction (STEMI), the incidence of major adverse cardiovascular events (MACE) following STEMI has not significantly decreased.
Zeyan Liu, Jinbo Wang, Yanfang Yang, Jinglin Cheng, Min Yang, Ye Zhang   +5 more
doaj   +1 more source

Effectiveness and safety of chest pain assessment to prevent emergency admissions: ESCAPE cluster randomised trial [PDF]

Objective To determine whether introducing chest pain unit care reduces emergency admissions without increasing reattendances and admissions over the next 30 days. Design Cluster randomised before and after intervention trial.
Capewell, S, Cross, E, Goodacre, S, Lewis, C, Nicholl, J   +4 more
core  

Neck‐vein thrombosis during spaceflight

British Journal of Clinical Pharmacology, EarlyView.
Spaceflight imposes unique environmental challenges, including weightlessness, increased radiation exposure and confinement, which can lead to unexpected health effects. One such example is neck‐vein thrombosis, a condition rarely seen on Earth without predisposing factors such as venous catheters or infections.
Ulrich Limper, Jens Jordan
wiley   +1 more source

Successfully treated mandibular osteomyelitis by TNF inhibitor in SAPHO syndrome

Arthritis &Rheumatology, Accepted Article.
Seiya Oba, Tadashi Hosoya, Kota Yokoyama, Hirofumi Tomioka, Hiroyuki Harada, Shinsuke Yasuda   +5 more
wiley   +1 more source

Morphology of the sternoclavicular joint and its microanatomical changes in response to osteoarthritic degeneration

Clinical Anatomy, EarlyView.
Abstract Although the sternoclavicular joint shares structural similarities with the knee and hip joints as a diarthrodial joint, its biomechanics differ significantly due to its non‐weight‐bearing nature. Nevertheless, it is subject to considerable loading, leading to increased susceptibility to osteoarthritis, a prevalent condition characterized by ...
Sophie Mok, Yousef Almajed, Abdulaziz Alomiery, Roger Soames, Abduelmenem Alashkham   +4 more
wiley   +1 more source

The Myofascial Continuum: Anatomical Insights Into Noncardiac Chest Pain

Clinical Anatomy, EarlyView.
ABSTRACT Angina, commonly known as chest pain, is the primary symptom of ischemic heart disease and can also present as pain in the neck, shoulder, jaw, arm, or back. Noncardiac chest pain (NCCP) is a common disorder with various causes, marked by recurrent chest pain that mimics ischemic heart pain.
Prabu Raja G, Rohini Punja, Antony Marie Cruz, Anupama Prabhu   +3 more
wiley   +1 more source

Cardiac Magnetic Resonance Stress Perfusion Imaging for Evaluation of Patients With Chest Pain

Journal of the American College of Cardiology, 2019
Raymond Y. Kwong, Y. Ge, K. Steel, S. Bingham, Shuaib M. Abdullah, K. Fujikura, Wei Wang, A. Pandya, Yi-Yun Chen, J. R. Mikolich, Sebastian Boland, Andrew E. Arai, W. Bandettini, S. Shanbhag, Amit R. Patel, Akhil Narang, A. Farzaneh-Far, Benjamin Romer, J. Heitner, J. Ho, Jaspal Singh, C. Shenoy, Andrew Hughes, Steve W. Leung, Meera Marji, Jorge A. Gonzalez, S. Mehta, Dipan J. Shah, Dany Debs, S. Raman, A. Guha, Victor A. Ferrari, J. Schulz-Menger, R. Hachamovitch, M. Stuber, Orlando P. Simonetti   +35 more
semanticscholar   +1 more source