Results 81 to 90 of about 791,591 (290)

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

Advanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang   +9 more
wiley   +1 more source

Role of Incentive Spirometry in Trauma Patients Managed with Tube Thoracostomy

Journal of the Dow University of Health Sciences, 2015
Objectives: To assess the role of incentive spirometry in trauma patients managed with tube thoracostomy in preventing postoperative pulmonary complications. Trauma injury accounts for 30% of all life years lost in the U.S.4 Chest trauma constitutes the
Naveed Ali Khan, Ata ur Rehman, Iqra Khan, Khursheed A. Samo, Amjad Siraj Memon   +4 more
doaj   +2 more sources

Red blood cell distribution width in patients with limb, chest and head trauma [PDF]

, 2017
Introduction : This study investigated the values of red blood cell distribution width (RDW), an emerging and independent predictor of morbidity and mortality, in patients with limb, chest and head trauma.
Giuseppe Lippi, Mitaritonno, Michele, Buonocore, Ruggero, BOVO, CHIARA, Ruggero Buonocore, Michele Mitaritonno, LIPPI, Giuseppe, Chiara Bovo, Gianfranco Cervellin, Cervellin, Gianfranco   +9 more
core   +1 more source

Rapid‐Forming Conductive Antifouling Hydrogel Coating Enables Magnetically Guided Electrochemical POCT for Direct at‑Home Blood Testing

Advanced Science, EarlyView.
The SPG‐MpECis electrochemical POCT platform developed in this study enables direct detection of biomarkers in complex biological samples such as serum and fingerstick blood, demonstrating high concordance with results from clinical reference methods and holding broad potential for at‐home testing applications.
Menghan Li, Kai Su, Ruiwei Hu, Ke Gao, Yuanjie Liu, Lu Zhang, Ningke Fan, Yirong Chen, Wei Cheng, Shijia Ding, Haiping Wu   +10 more
wiley   +1 more source

The Importance of Electrocardiographic Screening in Cardiac Contusion after Blunt Chest Trauma: Case Reports

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2013
Tracking and monitoring of patients with blunt chest trauma, especially blunt trauma is very important. As in all kinds of trauma, cardiac contusion in isolated chest trauma may result in acute coronary syndromes.
Keziban Ucar Karabulut, Huseyin Narci, Basar Cander, Mehmet Gul, Cetin Duman   +4 more
doaj  

Spectrum of MDCT findings in blunt chest trauma patients at a tertiary health care University Hospital: A single-centre experience

The Egyptian Journal of Radiology and Nuclear Medicine, 2018
Purpose: Evaluate MDCT findings in patients with blunt chest trauma with a demographic evaluation of number and percentage of each pattern over 6 months at University Hospital.
Youssriah Yahia Sabri, MD, Mona Ahmed Fouad Hafez, MD, Yasmine Hamdy El Hinnawy, MD, Mohamed Abdel Moneim Salim Mostafa, MSc   +3 more
doaj   +1 more source

Specifications of Traumatized Patients Referring to Fatemi Hospital of Ardabil, 2007-8 [PDF]

Background & Objectives: Trauma is one of the major causes of morbidity and mortality in the world and it puts a great deal of financial pressure on the health systems.
رستمی, خلیل, امانی, فیروز, حبیب زاده, شهرام   +2 more
core  

Developing Highly Effective Nanoparticle mRNA Therapeutic for Pediatric Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng, Wen Gao, Jonathan Do, Danli Lu, Ying‐Wei Lan, Andreas Damianos, Gautam Verma, Ali Al Siraj, Isabella Lowry, Lance Peter, Nicholas E. Banovich, Fei Sun, Hua He, Tanya V. Kalin, Vladimir V. Kalinichenko   +14 more
wiley   +1 more source

Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC) : a pragmatic, cluster randomised controlled trial [PDF]

, 2014
Background: Mechanical chest compression devices have the potential to help maintain high-quality cardiopulmonary resuscitation (CPR), but despite their increasing use, little evidence exists for their effectiveness.
Cooke, MW, Deakin, Charles D., Whitfield, R, Lamb, Sarah E, Perkins, Gavin D., Gates, S, Lamb, S. E., Smyth, M, Slowther, Anne, Deakin, CD, Lamb, Sarah E., Pocock, H, Black, JJM, Wright, John, Han, K, Horton, J, Whitfield, Richard, Black, John J. M., Black, John J M, Han, Kyee, Cooke, Matthew, Gates, Simon, Lamb, Sarah, Horton, Jessica, Wright, J, Pocock, Helen, Lamb, SE, Lal, R, Williams, A, Quinn, Tom, Woollard, M, Lall, Ranjit, Paramedic trial Collaborators,, Slowther, Anne-Marie, Black, JJ, Cooke, Matthew W., Williams, Amanda, Slowther, AM, Carson, A, Perkins, GD, Smyth, Michael A., Lall, R, Carson, Andy, Cooke, Matthew W, Smyth, Mike, Black, John J.M., Woollard, Malcolm, Perkins, Gavin D, Quinn, T, Deakin, Charles D   +49 more
core   +1 more source