Results 131 to 140 of about 2,714 (212)

Pathophysiological and Molecular Features of DXd ADC‐Related Interstitial Pneumonitis in Cynomolgus Monkeys

open access: yesCancer Science, EarlyView.
An interstitial lung disease model for DXd antibody‐drug conjugates was established in cynomolgus monkeys by weekly dosing of a non‐targeting DXd ADC. Integrated analysis of bronchoalveolar lavage fluid–derived extracellular vesicle proteomics and lung single‐cell RNA sequencing reveals cell‐type‐resolved molecular features of DXd ADC‐related lung ...
Kazuyoshi Kumagai   +5 more
wiley   +1 more source

Phenotypic Expansion and Molecular Implications in Recessive FUZ‐Related Ciliopathy

open access: yesClinical Genetics, EarlyView.
Our patient with homozygous FUZ p.Arg234Trp, potentially altering FUZ‐CPLANE2 interactions, presented with aorto‐pulmonary window, Hirschsprung disease, and shared phenotypes with previously reported ciliopathy patients. This report provides additional evidence for FUZ as a causative gene for ciliopathy, offering novel insights into the phenotype ...
Yosuke Ogawa   +4 more
wiley   +1 more source

HPV42 – a human papillomavirus classified as a low‐risk type with oncogenic potential

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low‐risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts.
Sven Niklas Burmann   +7 more
wiley   +1 more source

Outcomes of children and young people with cerebral palsy receiving long‐term respiratory support: A systematic review

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Outcomes of children with cerebral palsy receiving long‐term respiratory support. Abstract Aim To systematically review the current knowledge gap in, and impact of, long‐term respiratory support in children and young people (CYP) with cerebral palsy (CP). Method We searched six databases from inception until 30th January 2025.
Rajkumar Dhandayuthapani   +5 more
wiley   +1 more source

Laboratory Biology, Immature and Adult Morphology of Trichopria drosophilae (Perkins) (Hymenoptera: Diapriidae), Parasitoids of Drosophila Flies

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
This study investigates the laboratory biology and morphology of the parasitoid Trichopria drosophilae, which targets Drosophila flies, including the invasive Drosophila suzukii. Key findings include a detailed description of the parasitoid's egg, three larval instars, and pupal stage, as well as unique behaviors such as siblicide and encapsulation in ...
Alex Gumovsky   +3 more
wiley   +1 more source

No evidence of a decoy effect in bees: Rewardless flowers do not increase bumblebees' preference for neighbouring flowers

open access: yesEcological Entomology, EarlyView.
Many plants retain nectarless flowers; we tested whether these act as “decoys” for bees by making neighbouring rewarding flowers seem more valuable—a cognitive bias known as the decoy effect. The presence of decoy flowers did not shift bumblebee preferences between two equally rewarding inflorescences, and bees quickly learned to avoid these nectarless
Mélissa Armand   +3 more
wiley   +1 more source

Antimicrobial prescribing guidelines for feedlot cattle

open access: yes
Australian Veterinary Journal, EarlyView.
P Cusack   +4 more
wiley   +1 more source

Emerging Techniques in Minimally Invasive Surgery in Hematologic Malignancies

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Hematologic malignancies represent the most common cancers in children. While the mainstays of treatment are chemotherapy and potentially hematopoietic stem cell transplant, minimally invasive surgery (MIS) has a role in the diagnosis and management of complications related both to disease and therapy as well as common pediatric surgical ...
Alejandro Chara   +3 more
wiley   +1 more source

Postoperative Care and Management in Pediatric Hematology‐Oncology Patients

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Pediatric patients with hematologic and oncologic diseases often undergo surgical procedures as part of diagnosis and therapy. These include central venous catheter placements, tumor resections, lymph node and bone marrow biopsies, among others.
Shachi Srivatsa, Sara A. Mansfield
wiley   +1 more source

Evolving treatments for Sjögren disease: current approaches and emerging targets

open access: yesInternal Medicine Journal, EarlyView.
Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani   +3 more
wiley   +1 more source

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