New Pyridobenothiazolone Derivatives Display Nanomolar Pan‐Serotype Anti‐Dengue Virus Activity
A ligand‐based strategy is employed, starting from hit compound 2, to develop the C‐2 modified pyridobenzothiazolone 19 as a pan‐serotype nanomolar DENV‐1‐4 inhibitor. Investigations of the mechanism reveal the peculiar ability to abolish the infectivity of virions in a second infection.
Tommaso Felicetti+13 more
wiley +1 more source
How safe is it to discharge home patients with a chest tube in place? A narrative review of the literature. [PDF]
Minervini F+3 more
europepmc +1 more source
Trans-thoracic microwave coagulo-necrotic therapy for hepatic tumors without chest tube insertion
Yasuharu Ikeda+8 more
openalex +2 more sources
Advancing FIRES Treatment: The Potential of Intrathecal Dexamethasone
ABSTRACT Background Febrile infection‐related epilepsy syndrome (FIRES) is a rare, devastating epilepsy syndrome characterized by refractory status epilepticus following a febrile illness. Patient Description We describe a 12‐year‐old girl with FIRES who exhibited a remarkable clinical and electrographic response to intrathecal dexamethasone (IT‐DEX ...
Carol Park+10 more
wiley +1 more source
An alternative to chest tube thoracostomy equipment. [PDF]
Keskin H, Kuran E.
europepmc +1 more source
Effectiveness of Single Chest Tube vs Double Chest Tube Application Postdecortication: Prospective Randomized Controlled Study. [PDF]
Hart JM+7 more
europepmc +1 more source
Improved drainage with active chest tube clearance☆☆☆ [PDF]
Akira Shiose+7 more
openalex +1 more source
Ritonavir‐boosted atazanavir is a victim of drug–drug interaction with rifampicin, a key component of antitubercular treatment. In a recent dose escalation clinical trial, we showed that increasing atazanavir/ritonavir to 300/100 mg b.i.d. compensates for reduced drug exposure in plasma due to rifampicin, but the intracellular effects remained ...
Amedeo De Nicolò+16 more
wiley +1 more source
Comparative Analysis of Analog and Digital Chest Tube Drainage Systems Using a High-Fidelity 3D-Printed Neonatal Chest Model. [PDF]
Anzinger FX+6 more
europepmc +1 more source
Chest Tube Placement and Management: A Practical Review. [PDF]
Roebker JA+5 more
europepmc +1 more source