Pharmaceutical Equivalence of Film-Coated and Chewable Tablets: A Comparative Dissolution Study Using Pulverized Chewable Tablets [PDF]
PharmaceuticalsFamotidine is a histamine H2 receptor antagonist used in the treatment of gastrointestinal disorders. It is available in multiple formulations, including film-coated tablets, chewable tablets, oral suspension, and injections.
Sung-Up Choi
exaly +6 more sources
Formulation of novel niosomal repaglinide chewable tablets using coprocessed excipients: in vitro characterization, optimization and enhanced hypoglycemic activity in rats [PDF]
Drug Delivery, 2023 Repaglinide (RPG), a monotherapy insulin secretagogue used to treat diabetes mellitus-type II yet, it suffers from poor water solubility and variable bioavailability (∼ 50%) due to hepatic first pass metabolism.
Mahmoud Teaima, Mohamed El Nabarawi
exaly +4 more sources
Formulation Development of Albendazole-Loaded Self-Microemulsifying Chewable Tablets to Enhance Dissolution and Bioavailability [PDF]
Pharmaceutics, 2019 Albendazole is an anthelmintic agent with poor solubility and absorption. We developed a chewable tablet (200 mg drug equivalent), containing a self-microemulsifying drug delivery system (SMEDDS), with oral disintegrating properties.
Teerapol Srichana +2 more
exaly +4 more sources
Acceptance of oclacitinib maleate (Apoquel®) chewable tablets in client-owned dogs with allergic and atopic dermatitis [PDF]
BMC Veterinary Research, 2022 Background The oral acceptance of oclacitinib maleate (Apoquel®) chewable tablets administered twice daily for 7 days at the labeled dose range of 0.4–0.6 mg/kg was evaluated in 121 dogs treated at ten general practice veterinary clinics in the United ...
Marike Visser +4 more
doaj +2 more sources
Chewable tablets containing rape bee pollen and maca attenuate testosterone propionate–induced benign prostatic hyperplasia in Sprague–Dawley rats by regulating the gut microbiota and modulating the IL-6/JAK2/STAT3 signaling pathway [PDF]
Frontiers in MicrobiologyBackgroundBenign prostatic hyperplasia (BPH) significantly compromises patients' quality of life, has detrimental effects on both physical and mental well-being, and poses a substantial economic burden.
Xiaoqiang Huang +11 more
doaj +2 more sources
Field efficacy of fluralaner (Bravecto® chewable tablets) for preventing Babesia canis infection transmitted by Dermacentor reticulatus ticks to dogs [PDF]
Parasites & Vectors, 2023 Background The isoxazoline fluralaner is effective for prevention of Babesia canis transmission from infected Dermacentor reticulatus ticks to dogs for 84 days in a controlled environment.
Rafael Chiummo +8 more
doaj +2 more sources
Development of 3D printed dexamethasone chewable tablets for prophylaxis of chemotherapy-induced nausea and vomiting in children [PDF]
International Journal of Pharmaceutics: XDexamethasone (Dexa) is widely used for the prophylaxis of chemotherapy-induced nausea and vomiting. In pediatric patients, individual dosing often requires the manipulation of commercial tablets, leading to dose inaccuracies, higher treatment complexity
Adrin Dadkhah +8 more
doaj +2 more sources
A complete cross-over design evaluating canine acceptance of Carprieve® and Rimadyl® carprofen chewable tablets in healthy dogs [PDF]
BMC Veterinary Research, 2019 Background Osteoarthritis (OA) affects nearly 20% of all dogs greater than one year of age. Clinical signs include pain, discomfort, lameness, and ultimately lead to disability.
Diana M. A. Dewsbury +3 more
doaj +2 more sources
Chewable Tablets for Precise Unit Dosing of Animals. [PDF]
J Pharm InnovAbstract Introduction Peroral administration of preclinical drugs is commonly achieved through oral gavage or food formulations. However, oral gavage induces distress and is unsuitable for behavior studies, whereas food mixing and delivery are less precise. Therefore, we manufactured and tested
Landes RE +6 more
europepmc +4 more sources
Tadalafil-Loaded Self-Nanoemulsifying Chewable Tablets for Improved Bioavailability: Design, In Vitro, and In Vivo Testing [PDF]
Pharmaceutics, 2022 Yaser M Alahmadi +2 more
exaly +2 more sources