Results 151 to 160 of about 239,376 (290)

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

open access: yesCytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas   +5 more
wiley   +1 more source

The C‐Terminal Regions of TRAK Proteins Contain MIRO‐Independent Mitochondrial Localization Domains

open access: yesCytoskeleton, EarlyView.
ABSTRACT Current models suggest that MIRO GTPases anchor cytoskeletal motors to the mitochondrial outer membrane (MOM). However, our previous findings indicate that the unconventional myosin, MYO19, interacts with MIRO weakly and that a MIRO‐independent MOM‐localizing domain interacts more tightly with the MOM.
Lili Mitchell   +4 more
wiley   +1 more source

Association of Chewing Tobacco and the Risk of Breast Cancer in Indian Women: A Multicentre Case-Control Study. [PDF]

open access: yesInt J Breast Cancer
Moirangthem R   +15 more
europepmc   +1 more source

Oral Squamous Cell Carcinoma‐Risk Factors, Diagnosis, Treatment, and Prevention

open access: yesCancer Nexus, EarlyView.
ABSTRACT Oral squamous cell carcinoma (OSCC) usually originates from the precancerous lesions of oral mucosa and accounts for approximately 90% of oral cancers. In‐depth understanding of pathogenesis, hallmarks, and etiological factors is a crucial prerequisite for advancing the diagnosis and treatment for OSCC patients. This review aims to present the
Liping Wang   +4 more
wiley   +1 more source

Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cinnamon (Cinnamomum spp.) is used as a culinary spice and dietary supplement. A major constituent, cinnamaldehyde, was previously shown to inactivate cytochrome P450 (CYP) 2A6 in vitro. A mechanistic static model predicted an ~5‐fold increase in the AUC of the CYP2A6 substrates nicotine and letrozole.
Aiden‐Hung P. Nguyen   +8 more
wiley   +1 more source

Starving for Data: Eating Disorders Prevalence and Research Gaps in Southern Africa

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Studies reporting prevalence estimates of eating disorders in Southern Africa are scarce. To fill this gap, the present Research Forum reviews existing literature on the prevalence of eating disorders, including as assessed by clinical interviews, screeners, and self‐reported behaviors, among individuals in Southern Africa.
Bernou Melisse   +2 more
wiley   +1 more source

Modified Deep Lateral Wall Decompression Surgery in the Treatment of Thyroid‐Associated Ophthalmopathy: A Retrospective Evaluation

open access: yesEye &ENT Research, EarlyView.
ABSTRACT Background Thyroid‐associated ophthalmopathy (TAO) may lead to severe exophthalmos and dysthyroid optic neuropathy (DON), which can threaten visual function. Orbital decompression surgery is often required when medical therapy is insufficient; however, traditional deep lateral wall decompression techniques remain associated with several ...
Shuo Wu   +4 more
wiley   +1 more source

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