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Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Importance of balanced datasets with feature selection and ensemble methods on heart disease classification using distinctive machine learning techniques: a comparative analysis. [PDF]

Sci Rep
Ara J, Bhuiyan H, Roza II, Nahin ASM.
europepmc   +1 more source

Treatment Response Trajectories of Epipharyngeal Abrasive Therapy (EAT) in Chronic Nasopharyngitis: Phenotypic Classification Into Early, Delayed, and Non-Responders Based on ΔEAT With Outcome Stratification. [PDF]

Cureus
Hirobumi I.
europepmc   +1 more source

Debridement, Antibiotics, and Implant Retention (DAIR) Protocol for the Management of Early Periprosthetic Joint Infections: An Eight-Year Single-Centre Experience. [PDF]

J Clin Med
Grajek A, Chaberek S, Grzelecki D.
europepmc   +1 more source

Retrospective study on the effectiveness of clinical pharmacists' consultation in the management of carbapenem-resistant organisms infections. [PDF]

Front Pharmacol
Ma J, Li X, Liu X, Zhang Y, Zhang S.
europepmc   +1 more source

Hives in autonomic disorders: a cutaneous marker of a distinct symptom phenotype. [PDF]

Ann Med
Savigamin C, Chung T, Rebman AW, Larsen Y, Clark E, Cerquetti E, Kokorelis C, Dehghan P, Rowe PC, Adler BL.   +9 more
europepmc   +1 more source

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A Sequential Chi-Square Test

Theory of Probability & Its Applications, 1985
The author considers a sequence of discrete random variables \((X_ i)_{i=1,2,...}\) where the probability distribution for \(i>\theta\) is different from the one for \(i\leq \theta\). A sequential chi-square test is proposed for the hypotheses on the unknown parameter \(\theta\).
Germogenov, A. P., Ronzhin, A. F.
openaire   +1 more source

The Application of the Chi-Squared Test

The Mathematical Gazette, 1971
Suppose that we open a telephone directory and select any column which consists entirely of personal names. The last digit of each telephone number would seem to have no preferred value. For example, the middle column on p. 417 of the 1970 Newcastle upon Tyne directory contains 109 names, and the frequencies for 0,1,…, 9 are as follows.
openaire   +1 more source