Results 51 to 60 of about 910,710 (254)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Statistical Homogeneity Zoning of a High and Steep Slope Based on Chi-Square Test

Chemical Engineering Transactions, 2018
This paper aims to develop an objective and rational method for statistical homogeneity zoning of high and steep slopes. For this purpose, the fracture trace length was introduced to the statistical homogeneity zoning based on the statistical similarity ...
Ming Li, Shuochao Bao, Huiming Liu
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Relationship between Chinese medicine dietary patterns and the incidence of breast cancer in Chinese women in Hong Kong: a retrospective cross-sectional survey

Chinese Medicine, 2017
Background This retrospective cross-sectional study aimed to investigate the relationship between Chinese medicine (CM) dietary patterns (hot, neutral, and cold) and the incidence of breast cancer among Chinese women in Hong Kong.
Xiao Zheng, Jianping Chen, Ting Xie, Zhiyu Xia, Wings Tjing Yung Loo, Lixing Lao, JieShu You, Jie Yang, Kamchuen Tsui, Feizhi Mo, Fei Gao   +10 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Statistical insights from Romanian data on higher education [PDF]

Revista Română de Statistică, 2015
This paper aims to use cluster analysis to make a comparative analysis at regional level concerning the Romanian higher education. The evolution of higher education in post-communist period will also be presented, using quantitative traits.
Andreea Ardelean
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

NMR Thermal Control Subsystem Reliability Design and Verification Based on Chi-Square Test

Zhongguo yiliao qixie zazhi
The nuclear magnetic resonance (NMR) thermal control subsystem described in this paper is a newly developed platform-based thermal management solution. It presents critical challenges in system architecture design and core component selection. Therefore,
Tingwei LIU, Cunli ZHANG, Jie ZHOU, Gang HU   +3 more
doaj   +1 more source

Analysis of Paired Dichotomous Data: A Gentle Introduction to the McNemar Test in SPSS

Journal of MultiDisciplinary Evaluation, 2012
Background: Although McNemar Test is the most appropriate tool for analyzing pre-post differences in dichotomous items (e.g., “yes” or “no”, “correct” or “incorrect”, etc.), many scholars have noted the inappropriate use of Pearson’s Chi-square Test by ...
Omolola A. Adedokun, Wilella D. Burgess
doaj   +1 more source