Results 221 to 230 of about 9,650,040 (289)

Hollow Cu2O Nanozymes Enhance Probiotic Therapy for Colitis via Redox Homeostasis and TXNIP/NLRP3 Inflammasome Inhibition

Advanced Science, EarlyView.
Hollow cuprous oxide (H‐Cu2O) nanozymes feature enlarged catalytic surfaces for superior reactive oxygen species (ROS) scavenging. By efficiently neutralizing mucosal ROS, H‐Cu2O directly suppresses the TXNIP/NLRP3 inflammasome axis and restores intestinal epithelial barrier integrity.
Guangzhao Wang, Jialing Cao, Pengfei Li, Yujie Wang, Shiqi Lu, Kangliang Sheng, Shan Gao, Yongzhong Wang   +7 more
wiley   +1 more source

Corrigendum to 'Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant' [Biomaterials, 128 (2021), 121159]. [PDF]

Biomaterials
Gray LT, Raczy MM, Briquez PS, Marchell TM, Alpar AT, Wallace RP, Volpatti LR, Sasso MS, Cao S, Nguyen M, Mansurov A, Budina E, Watkins EA, Solanki A, Mitrousis N, Reda JW, Yu SS, Tremain AC, Wang R, Nicolaescu V, Furlong K, Dvorkin S, Manicassamy B, Randall G, Wilson DS, Kwissa M, Swartz MA, Hubbell JA.   +27 more
europepmc   +1 more source

PolyG Fibrils Coalesce Into Nuclear Ribbons That Engage Proteostasis Machinery in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
In NIID, expanded NOTCH2NLC repeats give rise to nuclear polyG inclusions. Tracer‐guided in situ cryo‐electron tomography enables cross‐scale structural analysis from mouse brain to native neuronal nuclei, revealing dense‐core/peripheral‐halo inclusions built from compact polyG ribbons.
Hui Dong, Yongcheng Pan, Zhiyao Tang, Yuxuan Yao, Guicong Zhang, Junpu Wang, Haonan Xiao, Yun Tian, Beisha Tang, Dan Li, Qiang Guo, Ruijun Tian, Qiong Liu, Cong Liu   +13 more
wiley   +1 more source

Serious Illness Communication in Emergency Medicine: A Badge Card for Practice and Teaching. [PDF]

AEM Educ Train
Putman M.
europepmc   +1 more source

SIZ1‐Mediated SUMOylation of LBD29 Recruits ARF7 to Fine‐Tune Auxin Signaling in Lateral Root Development

Advanced Science, EarlyView.
Our findings establish SUMOylation as a key post‐translational control layer in auxin signaling. We show that SIZ1‐mediated SUMOylation of LBD29 promotes its association with ARF7, stabilizing a transcriptional hub that governs lateral root development.
Jiaxuan Sui, Qianlan Yin, Yiying Chen, Liping Zhang, Xiuyuan Yu, Qianqian Yu, Zhaojun Ding, Xiangpei Kong   +7 more
wiley   +1 more source

Plastic Bowing of the Pediatric Tibia is Extraordinarily Rare and Not Represented in the Literature, the Unicorn of Pediatric Fractures: A Case Report. [PDF]

J Orthop Case Rep
Goedderz C, Luiso M, Sarwark JF.
europepmc   +1 more source

A High‐Resolution Self‐Powered Angular Displacement Sensor Based on Triboelectric Nanogenerator With Time‐Grating

Advanced Science, EarlyView.
A self‐powered phase‐encoding sensing paradigm enables direct motion‐to‐time information conversion, providing a compact and autonomous strategy for high resolution angular displacement measurement. ABSTRACT In modern manufacturing and engineering, angular displacement sensors are crucial for motion control and feedback systems in Electromechanical ...
Shuxian Wang, Donghang An, Shiyou Liu, Zhiyi Wu   +3 more
wiley   +1 more source

Physiologically Based Pharmacokinetic Modeling to Characterize the Disposition of Topiramate in Children with and without Obesity. [PDF]

J Clin Pharmacol
Maglalang PD, Gonzalez D, Muller WJ, Hornik CD, Goldstein SL, Rathore M, Ford JL, Balevic SJ, Sinha J, Edginton A, Greenberg RG, Benjamin DK, Chen JY, Zimmerman KO, Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee.   +14 more
europepmc   +1 more source

Non-fatal firearm violence across 17 US cities using police dashboard data, 2020-2025. [PDF]

Prev Med Rep
Benjamins MR, De La Huerta C, Saiyed NS, Offstein M, Gutierrez-Kapheim M, Wolf A.   +5 more
europepmc   +1 more source

Digital Health Connectivity as Infrastructure for Rural Cardiovascular Equity. [PDF]

JACC Adv
Johnson AE, Magnani JW, Echols MR, Kitsiou S, Bhatt AB.   +4 more
europepmc   +1 more source