Results 111 to 120 of about 461,979 (350)

Fully Humanized Bispecific T Cell Engager Shows Potent Activity in Central Nervous System and Peripheral Tumors

Advanced Science, EarlyView.
This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy, Angela Martin‐Regalado, Benedikt E. Haupt, Jacob R. Pogue, Aditi Thakur, Manuel Fierro Cota, Markella Zannikou, Sol Misener, Vera P. Krymskaya, Kathleen McCortney, Jason Miska, Craig Horbinski, Dmitri Simberg, Maciej S. Lesniak, Charles D. James, Roger Stupp, Irina V. Balyasnikova   +16 more
wiley   +1 more source

Embryonic heat conditioning induces paternal heredity of immunological cross- tolerance: coordinative role of CpG DNA methylation and miR-200a regulation

Frontiers in Immunology
BackgroundEnhancing an organism’s survival hinges on the development of balanced and adaptable stress response systems. While the initial stress-response set-points in the hypothalamus may be genetically determined, they are further influenced by ...
Padma Malini Ravi, Tatiana Kisliouk, Shelly Druyan, Amit Haron, Mark A. Cline, Elizabeth R. Gilbert, Noam Meiri   +6 more
doaj   +1 more source

Categories, concepts, and calls : auditory perceptual mechanisms and cognitive abilities across different types of birds. [PDF]

, 2013
Although involving different animals, preparations, and objectives, our laboratories (Sturdy's and Cook's) are mutually interested in category perception and concept formation.
Cook, Robert, Guillette, Lauren, Hahn, Allison, Hoeschele, Marisa, Sturdy, Christopher   +4 more
core   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Distinct molecular profile of the chick organizer as a stem zone during axial elongation

Open Biology
The vertebrate organizer plays a crucial role in building the main (antero-posterior) axis of the embryo: it neuralizes the surrounding ectoderm, and is the site of emigration for cells making axial and paraxial mesendoderm during elongation.
Timothy R. Wood, Iwo Kucinski, Octavian Voiculescu   +2 more
doaj   +1 more source

Chick genomics [PDF]

genesis, 2013
Burt, David W., Farlie, Peter G.
openaire   +4 more sources

Violation of cell lineage restriction compartments in the chick hindbrain [PDF]

, 1994
Previous cell lineage studies indicate that the repeated neuromeres of the chick hindbrain, the rhombomeres, are cell lineage restriction compartments. We have extended these results and tested if the restrictions are absolute. Two different cell marking
Birgbauer, Eric, Fraser, Scott E.
core  

Nondirected axonal growth on basal lamina from avian embryonic neural retina [PDF]

, 1987
The vitreous surface of the embryonic avian retinal neuroepithelium was isolated by mechanical disruption of the retina mounted between 2 adhesive substrata.
Halfter, W., Kröger, Stephan, Reckhaus, W.   +2 more
core   +1 more source

Ion‐Pair‐Tuned Ionogels for Broad‐Range Linear Pressure Sensing

Advanced Science, EarlyView.
Ionogels engineered through ion‐pair tuning extend the linear sensing range of capacitive pressure sensors. By balancing ionic mobility and polarizability within the polymer matrix, this approach mitigates dielectric saturation and maintains a stable pressure response across a broad operating range.
Hyeonseo Joo, Tianhao Yu, Yumin Dai, Seokkyoon Hong, Axel González Cornejo, Tristan Michael Long, Sang Mok Park, Pete S. Kollbaum, Edgar Bolívar‐Nieto, Young L. Kim, Dong Rip Kim, Chi Hwan Lee   +11 more
wiley   +1 more source

Evaluation of the Effect of Bacillus Subtilis and Pediococcus Acidilactici Mix on Serum Biochemistry, Growth Promotation of Body and Visceral Organs in Lohmann Brown Chicks [PDF]

Brazilian Journal of Poultry Science
Recently the use of antibiotic growth promoter (AGPs) in poultry feed is banned in China, leading to the increasing demand for AGPs substitutes. Probiotics have been considered as a potential substitute.
W Yu, X Hao, W Zhiyue, Y Haiming, X Lei
doaj   +2 more sources