Results 21 to 30 of about 26,455 (242)

PD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy

Advanced Science, EarlyView.
The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.
Huixin Gao, Lijuan Lu, Xiaoxiao Xiong, Yi Li, Donghui Hu, Duo Zhang, Zhiwei Feng, Cong Liu, Nannan Liu, Xiaoli Li, Jizhou Tan, Ting Liu, Ling Peng, Lu Lu, Huiyi Feng, Yan Zhong, Guisen Tan, Zhicheng Zhang, Liqin Huang, Chao Su, Ying Xue, Shuo Song, Wenxia Fan, Wei Wang, Fan Zou   +24 more
wiley   +1 more source

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous–venous extracorporeal membrane oxygenation (VV‐ECMO): A case report

British Journal of Clinical Pharmacology, EarlyView.
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart, Emiel Leegwater, Thomas H. Ottens, Emile F. Schippers, Erik B. Wilms, David M. Burger, Cees van Nieuwkoop, Liesbeth B. E. Bosma   +7 more
wiley   +1 more source

Antioxidant and Cytotoxic Properties of Piper spp. Volatile Oils That Inhibit Pathogenic Microorganisms

Flavour and Fragrance Journal, EarlyView.
The samples were fungicidal against Candida, with MICs ranging from 62.5 to 250 μg/mL, and fungistatic against Penicillium adametzii, Aspergillus flavus and A. niger, with MICs of 1000 μg/mL. The volatile oils of Piper aduncum and Piper marginatum reduced the viability of MDA‐MB231 cells.
Midiã R. Oliveira, Ely D. Alfaia Neto, Carlos Eduardo C. Alves, Renata Galvão de Azevedo, Alice F. Gomes, Flávia Juliana Reis de Sousa, Juan Campos de Oliveira, Larissa Raquel S. Maciel, Gemilson S. Pontes, Ari F. Hidalgo, Antonia Q. L. Souza, Rita C. Saraiva Nunomura   +11 more
wiley   +1 more source

Immunizations - Not Just for Kids [PDF]

, 2007
Immunizations/vaccinations are beneficial for most people of all ages. Yet the mistaken belief persists that, with the exception of the flu vaccine, children should be the primary recipients of this important area of primary disease prevention.
Harrison G. Bloom
core  

Health Advice from Internet Discussion Forums: How Bad Is Dangerous? [PDF]

, 2016
Background: Concerns over online health information–seeking behavior point to the potential harm incorrect, incomplete, or biased information may cause. However, systematic reviews of health information have found few examples of documented harm that can
Bansil, P, Biermann, JS, Chris Watkins, Cole, J, Crocco, AG, Dorothea Kleine, Eysenbach, G, Eysenbach, G, Impicciatore, P, Jennifer Cole, Laurillard, D, Schwartz, KL, Suarez-Almazor, ME, Sundar, S, Sunstein, TA   +14 more
core   +2 more sources

Association of Chronic Diseases With Herpes Zoster in China: A Nationwide Population‐Based Survey

Health Care Science, EarlyView.
Chronic disease was associated with elevated herpes zoster risk (aOR = 1.84, 95% CI: 1.51–2.24). Among 14 chronic conditions, heart disease showed the strongest association (aOR = 2.91, 95% CI: 2.07–4.10), followed by diabetes (aOR = 2.04, 95% CI: 1.48–2.80) and hypertension (aOR = 1.89, 95% CI: 1.47–2.42).
Wenhui Zhu, Yiqi Xia, Yanran Wang, Zhenyu Shi, Yang Shen, Chengsen Cui, Jinxu Ai, Yemin Yuan, Xin Ye, Dawei Zhu, Ping He   +10 more
wiley   +1 more source

A Model Infectious Disease Curriculum for Fourth Grade Students: Integrating Prevention and Education Concepts in the Classroom [PDF]

, 2006
Despite the significant need for prevention education and updated disease curricula in elementary schools, there is a deficit of model units, lesson plans, and activities at the fourth grade level.
Downie, Diane Loreli
core   +1 more source

Prevalence of a history of prior varicella/herpes zoster infection in multiple sclerosis [PDF]

, 2017
Varicella zoster virus (VZV) infection has been implicated in multiple sclerosis (MS), but direct causal involvement has been disputed. Nevertheless, knowledge of VZV exposure is important, given the risk of serious complications of first exposure while ...
A Ascherio, A Compston, A Manouchehrinia, A Nardone, Ali Manouchehrinia, AM Arvin, AM Arvin, BA Singer, BK Kleinschmidt-DeMasters, Cris S. Constantinescu, D Bourdette, D Gilden, D Gilden, DM Fleming, Fouzia Jabeen, G Ordonez, H Reiber, Huner Kareem, J Brettschneider, J Breuer, J Sotelo, J Sotelo, J Sotelo, JH Kang, Judith Breuer, Keith Neal, M Ito, Oltita P. Jerca, PA Maple, R Kohlmann, RA Marrie, Rachelle Shafei, Radu Tanasescu, RT Ross, RT Ross, S Sawcer, S Venkatachalapathy, William Irving   +37 more
core   +2 more sources

Chickenpox

Russian Pediatric Journal, 2023
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openaire   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source