Results 71 to 80 of about 26,279 (296)

Severe chest allodynia as an unusual first presentation of hydatid disease. A case report [PDF]

, 2019
Background: Cystic echinococcosis (CE) is a worldwide zoonosis and the liver is the most commonly affected organ. Clinical manifestations range from completely asymptomatic cysts to a potential lethal cyst rupture and anaphylaxis.
Caruso, Damiano, Coluzzi, Flaminia, Ettorre, Giuseppe Maria, Goletti, Delia, Meniconi, Roberto Luca, Petrone, Linda, Rivosecchi, Flaminia   +6 more
core   +1 more source

Differences in Dynamics of Specific Antinuclear Antibodies and Their Susceptibility to B Cell–Targeting Treatment in Patients With Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective The presence of antinuclear antibodies (ANAs) is characteristic for systemic lupus erythematosus (SLE). Antibody dynamics over time are thought to reflect the cellular source of ANAs and their therapeutic targetability. Anti–double‐stranded DNA (anti‐dsDNA) is the most prevalent and well‐studied of all ANAs, and fluctuations in anti‐dsDNA ...
Hugo J. van Dooren, Mieke van Schaik, Annemarie L. Dorjée, Eline J. Arends, Meggan Mackay, Laura Cooney, David A. Fox, David Wofsy, Dawn Smilek, Cynthia Aranow, Maria Dall'Era, Tom W. J. Huizinga, Cees van Kooten, René E. M. Toes, Betty Diamond, Y. K. Onno Teng, Jolien Suurmond   +16 more
wiley   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Social Phobia Is Associated with Delayed Onset of Chickenpox, Measles, and Mumps Infections. [PDF]

, 2016
Evidence showing that infectious diseases in childhood play an important role in the etiopathogenesis of neurodevelopmental and other mental disorders is growing. The aim of this study was to explore the timing of common childhood diseases in early-onset
Ajdacic-Gross, V., Aleksandrowicz, A., Castelao, E., Kawohl, W., Lieb, R., Mutsch, M., Müller, M., Preisig, M., Rodgers, S., Rössler, W., Vandeleur, C., von Känel, R.   +11 more
core   +3 more sources

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Chickenpox: an ageless disease [PDF]

BMJ Case Reports, 2017
A 97-year-old woman presented with 4-day history of vesicular rash, initially at the feet but then spread up to the thighs bilaterally, abdomen and trunk. The initial differentials included bullous pemphigus and cellulitis by the emergency department. She was then managed as bullous pemphigus by the acute medical team and started on high-dose steroids,
Nan Ma, Aza Abdulla, Annalan M D Navaratnam, Maria Farrukh   +3 more
openaire   +3 more sources

Populations Addressed in Vaccines Approved via the European Medicines Agency

Clinical Pharmacology &Therapeutics, EarlyView.
Therapeutic and prophylactic agents require robust evidence before patient use. Randomized controlled trials are essential for evaluating safety and efficacy but often exclude specific populations that are also targets for the intervention. This study assessed which populations are included in vaccine registration studies and/or addressed in label ...
Débora D. Gräf, Lukas Westphal, Jonathan Kimmelman, Christine E. Hallgreen   +3 more
wiley   +1 more source

Improving Skin Condition Classification with a Visual Symptom Checker Trained using Reinforcement Learning

, 2019
We present a visual symptom checker that combines a pre-trained Convolutional Neural Network (CNN) with a Reinforcement Learning (RL) agent as a Question Answering (QA) model. This method increases the classification confidence and accuracy of the visual
M Rotmensch, ML Puterman, RS Sutton, V Mnih, Y Chali   +4 more
core   +1 more source

Health Advice from Internet Discussion Forums: How Bad Is Dangerous? [PDF]

, 2016
Background: Concerns over online health information–seeking behavior point to the potential harm incorrect, incomplete, or biased information may cause. However, systematic reviews of health information have found few examples of documented harm that can
Bansil, P, Biermann, JS, Chris Watkins, Cole, J, Crocco, AG, Dorothea Kleine, Eysenbach, G, Eysenbach, G, Impicciatore, P, Jennifer Cole, Laurillard, D, Schwartz, KL, Suarez-Almazor, ME, Sundar, S, Sunstein, TA   +14 more
core   +2 more sources

Exploring the Potential and Advancements of Circular RNA Therapeutics

Exploration, EarlyView.
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang, Lianqing Wang, Chunbo Dong, Jialong Liu, Guoxin Cui, Shan Gao, Zhida Liu   +6 more
wiley   +1 more source