Metaplasia in the Stomach Arises From Gastric Chief Cells [PDF]
Cellular and Molecular Gastroenterology and Hepatology, 2017 The development of intestinal-type gastric cancer is preceded by loss of parietal cells (oxyntic atrophy) and the induction of metaplastic cell lineages in the gastric mucosa.
Jason C. Mills, James R. Goldenring
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Elevated stress response marks deeply quiescent reserve cells of gastric chief cells [PDF]
Communications Biology, 2023 Gastrointestinal tract organs harbor reserve cells, which are endowed with cellular plasticity and regenerate functional units in response to tissue damage.
Daisuke Shiokawa +8 more
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Dynamic role of gastric stem cells and chief cells in precancerous lesions of gastric cancer: global knowledge mapping and emerging trends based on bibliometric analysis from 2004 to 2024 [PDF]
Frontiers in OncologyBackgroundGastric stem cells (GSCs) and chief cells are vital for maintaining gastric epithelial homeostasis. However, under pathological conditions, these cells undergo significant functional changes, contributing to the progression of precancerous ...
Chen Wang +3 more
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The role of ESRRA and JUNB in oxyphil cells: insights from spatial transcriptomics and single-cell transcriptomics in uremic secondary hyperparathyroidism [PDF]
Biology DirectOxyphil cells are a primary cellular component of the parathyroid gland. Due to the limitations of techniques for separating oxyphil cells from chief cells, the characteristics and functions of oxyphil cells in uremic secondary hyperparathyroidism (SHPT)
Zeyu Zhang +4 more
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Postnatal developmental studies on the parathyroid gland of male Guinea pig with relation to bone formation [PDF]
Benha Veterinary Medical Journal, 2022 Blood calcium level can be controlled by the action of parathyroid gland on the bone via parathyroid hormone that responsible for bone mineralization. The study aimed to demonstrate the developmental histological structure of parathyroid gland and bone ...
Aya Tantawy +3 more
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Endoscopic Resection for Gastric Adenocarcinoma of the Fundic Gland Type: A Case Series
The Korean Journal of Gastroenterology, 2023 The fundic gland type (GA-FG) of gastric adenocarcinoma is a rare variant of gastric cancer recently included in the 5th edition of the World Health Organization’s classification of digestive system tumors.
Hwa Jin Lee +5 more
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Loss of Corpus-Specific Lipids in Helicobacter pylori-Induced Atrophic Gastritis
mSphere, 2021 Helicobacter pylori colonization of the stomach is a strong risk factor for the development of stomach cancer and peptic ulcer disease. In this study, we tested the hypothesis that H.
Aung Soe Lin +12 more
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Gastric Adenocarcinoma of Fundic Gland Type Treated by Endoscopic Submucosal Dissection [PDF]
The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2021 Gastric adenocarcinoma of fundic gland type is known to originate from the gastric mucosa of the fundic gland region without intestinal metaplasia. It is difficult to detect during endoscopy and diagnose histopathologically.
Yong Bo Park +5 more
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SOX9 Governs Gastric Mucous Neck Cell Identity and Is Required for Injury-Induced MetaplasiaSummary
Cellular and Molecular Gastroenterology and Hepatology, 2023 Background & Aims: Acute and chronic gastric injury induces alterations in differentiation within the corpus of the stomach called pyloric metaplasia. Pyloric metaplasia is characterized by the death of parietal cells and reprogramming of mitotically
Spencer G. Willet +8 more
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Decrease in MiR-148a Expression During Initiation of Chief Cell TransdifferentiationSummary
Cellular and Molecular Gastroenterology and Hepatology, 2020 Gastric chief cells differentiate from mucous neck cells and develop their mature state at the base of oxyntic glands with expression of secretory zymogen granules.
Takahiro Shimizu +5 more
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