Results 21 to 30 of about 7,027 (250)

The ISCIP Analyst, Volume V, Issue 9 [PDF]

open access: yes, 2000
This repository item contains a single issue of The ISCIP Analyst, an analytical review journal published from 1996 to 2010 by the Boston University Institute for the Study of Conflict, Ideology, and ...
Burk, Nicholas   +9 more
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Projects arranging supreme authority Russian Orthodox Church middle of the XIX century [PDF]

open access: yesВестник Православного Свято-Тихоновского гуманитарного университета: Серия ИИ. История, история Русской Православной Церкви, 2012
The article deals with the projects of the arranging of the supreme church management. The author makes the analysis of the projects on the base of a sources study. Some of them were introduced to a scientific historiography for the first time.
Bezhanidze Georgii
doaj  

The Bill of Rights and the Emerging Democracies [PDF]

open access: yes, 2002
Today, the influence of the US Bill of Rights can be traced through its remote offspring, including the Helsinki Agreement, the German Basic Law, the post-war French constitutions, and the European Convention on Human Rights.
Kurczewski, Jacek, Sullivan, Barry
core   +1 more source

Public authorities as "victims" under the Human Rights Act [PDF]

open access: yes, 2005
ONE feature of the current debate concerning the term “public authority” in the Human Rights Act 1998 is a rule to the effect that public authorities are not themselves capable of having and enforcing Convention rights.
Davis, Howard
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Acquisition and retention of DNA and fingerprint data in Scotland [PDF]

open access: yes, 2009
This review examines the current legislation and practices in relation to the acquisition and retention of fingerprint and DNA data in Scotland. Three main issues were under consideration: given that law and practice in relation to DNA and fingerprints ...
Fraser, Jim   +1 more
core  

Policing the police in the United Kingdom [PDF]

open access: yes, 2005
In the three jurisdictions of the United Kingdom, the specialized mechanisms for dealing with complaints against the police do not conform to one single model, and they have varying degrees of external involvement and oversight.
Seneviratne, M
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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