Results 111 to 120 of about 79,107 (279)

Zika virus: New clinical syndromes and its emergence in the western hemisphere [PDF]

open access: yes, 2016
Zika virus (ZIKV) had remained a relatively obscure flavivirus until a recent series of outbreaks accompanied by unexpectedly severe clinical complications brought this virus into the spotlight as causing an infection of global public health concern.
Brazilian Medical Genetics Society–Zika Embryopathy Task Force   +9 more
core   +3 more sources

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

open access: yesMedicinal Research Reviews, Volume 45, Issue 6, Page 1850-1882, November 2025.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro   +5 more
wiley   +1 more source

Perinatal chikungunya in twins

open access: yesJournal of Pediatric Neurosciences, 2016
We report a case of vertically transmitted chikungunya infection in heterozygous twin neonates presenting as seizures, encephalopathy, midfacial hyperpigmentation, anemia, and thrombocytopenia. This could be considered as a rare cause of neonatal seizure and identification would help in appropriate management.
Vikneswari Karthiga   +2 more
openaire   +4 more sources

Bone erosions and joint damage caused by chikungunya virus: a systematic review

open access: yesRevista da Sociedade Brasileira de Medicina Tropical
Background: Chikungunya fever is an emerging global infection transmitted by Aedes mosquitoes that manifests as an acute febrile illness with joint pain and can lead to chronic arthritis.
José Kennedy Amaral   +2 more
doaj   +1 more source

Divergent Delivery and Expression Kinetics of Lipid and Polymeric Nanoparticles across mRNA Modalities

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
Self‐amplifying (saRNA), linear (linRNA), and circular (circRNA) mRNAs are compared under standardized conditions using lipid nanoparticles (LNPs) and pABOL polymer. saRNA achieved superior expression, while linRNA and circRNA performance varied based on untranslated region elements and delivery method.
Irafasha C. Casmil   +12 more
wiley   +1 more source

First report of Chikungunya virus infection in Nepal

open access: yesJournal of Infection in Developing Countries, 2014
Chikungunya virus is an emerging arboviral disease that has been spreading rapidly across south Asia in recent years. Until recently, no chikungunya cases have been reported in Nepal.
Sher Bahadur Pun   +2 more
doaj   +1 more source

Design Strategies for Novel Lipid Nanoparticle for mRNA Vaccine and Therapeutics: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 6, Issue 10, October 2025.
This review summarizes strategies to optimize lipid nanoparticles (LNPs) for improved targeting, endosomal escape, and safety. It highlights mRNA design, alternative delivery systems, and recent therapeutic advances across infectious diseases, cancer, and drug applications.
Xiaochi Li   +7 more
wiley   +1 more source

Lessons learned exploiting a multi‐year large‐scale data set derived from operational quality assessment of mosquito larval treatments in rain catch basins

open access: yesPest Management Science, Volume 81, Issue 10, Page 6630-6638, October 2025.
Results highlight opposite associations between percentages of positive rain catch basins treated with diflubenzuron and Bacillus against mosquito larvae and/or pupae and the intervals between treatments and inspections, and spatial variability in vector control.
Chiara Virgillito   +11 more
wiley   +1 more source

Imported Chikungunya Virus Strains, Taiwan, 2006–2014

open access: yesEmerging Infectious Diseases, 2016
We identified 78 imported chikungunya cases in Taiwan during 2006–2014. Sixty-six (84.6%) cases were initially suspected to be dengue, which indicates the necessity for laboratory diagnostics in differentiation between dengue and chikungunya.
Cheng-Fen Yang   +5 more
doaj   +1 more source

Virtual dissection of Aedes aegypti mosquito using phase‐contrast synchrotron microtomography

open access: yesJournal of Microscopy, Volume 300, Issue 1, Page 68-76, October 2025.
Abstract In this paper, in‐line phase‐contrast synchrotron microtomography was used to study the morphology of adult Aedes aegypti. These specimens are vectors of several arboviruses, causing dengue, chikungunya, Zika and yellow fever. The morphological details of this insect species are still incomplete and insufficient.
Gabriela Sena   +15 more
wiley   +1 more source

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