Results 161 to 170 of about 89,546 (321)

Cytokines in Acute Chikungunya

open access: yesPLoS ONE, 2014
Acute chikungunya (CHIKV) is predominantly an acute onset of excruciatingly painful, self-limiting musculoskeletal (MSK) arbovirus illness and this was further reported by us during the 2006 Indian epidemic [Chopra et al. Epidemiol Infect 2012]. Selected serum cytokines profile in subjects within one month of onset of illness is being presented.Out of ...
Arvind Chopra   +2 more
openaire   +5 more sources

Corrigendum: Drug repurposing approach against chikungunya virus: an in vitro and in silico study

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Bhagyashri Kasabe   +8 more
doaj   +1 more source

Distinguishing patients with laboratory-confirmed chikungunya from dengue and other acute febrile illnesses, Puerto Rico, 2012-2015.

open access: yesPLoS Neglected Tropical Diseases, 2019
Chikungunya, a mosquito-borne viral, acute febrile illness (AFI) is associated with polyarthralgia and polyarthritis. Differentiation from other AFI is difficult due to the non-specific presentation and limited availability of diagnostics.
Luisa I Alvarado   +27 more
doaj   +1 more source

Pyriproxyfen Disrupts the Ongoing Spermatogenesis Wave in Danio rerio Potentially Mediated by Voltage‐Dependent Calcium Channels and Protein Kinase C

open access: yesJournal of Applied Toxicology, Volume 45, Issue 9, Page 1705-1719, September 2025.
ABSTRACT Pyriproxyfen (PPX) is an analog of the juvenile hormone from insects. Following our previous studies, for the ex vivo short‐term effect, we chose 10−9 M pyriproxyfen to analyze the morphology of spermatogenesis wave cells. In silico docking and ADMET (Absorption, Distribution, Metabolism, Excretion, Toxicity) studies were carried out to ...
Bruna Antunes Zaniboni   +5 more
wiley   +1 more source

PARP (Poly ADP‐ribose Polymerase) Family in Health and Disease

open access: yesMedComm, Volume 6, Issue 9, September 2025.
PARP family orchestrates ADP‐ribosylation to regulate genomic stability (DNA repair, telomeres) and metabolism (NAD⁺, glucose/lipid). Physiological roles sustain health; dysregulation drives pathologies: cancer (DNA repair addiction), neurodegeneration (parthanatos), cardiovascular disorders (hypertrophy/fibrosis), inflammation (dual role), and viral ...
Pengyuan Lei   +9 more
wiley   +1 more source

Ensuring successful introduction of Wolbachia in natural populations of Aedes aegypti by means of feedback control

open access: yes, 2015
The control of the spread of dengue fever by introduction of the intracellular parasitic bacterium Wolbachia in populations of the vector Aedes aegypti, is presently one of the most promising tools for eliminating dengue, in the absence of an efficient ...
Aronna, M. Soledad   +3 more
core   +1 more source

East/Central/South African Genotype in a Chikungunya Outbreak, Dhaka, Bangladesh, 2017

open access: yesEmerging Infectious Diseases, 2019
In 2017, an unprecedented increase in febrile illness was observed in Dhaka, Bangladesh. Real-time reverse transcription PCR confirmed that 603 (40.2%) of 1,500 cases were chikungunya fever.
Mizanur Rahman   +4 more
doaj   +1 more source

Zebrafish as a Versatile Model Organism: From Tanks to Treatment

open access: yesMedComm – Future Medicine, Volume 4, Issue 3, September 2025.
The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava   +9 more
wiley   +1 more source

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