Results 181 to 190 of about 7,461,305 (300)

Experiments on Nonlocal Fluid‐Flow Metamaterials

Advanced Science, EarlyView.
A nonlocal fluid‐flow metamaterial composed of standard microfluidic tubes and connectors is designed. Hence, the current of the system at one position depends on the gradient of fluid flow at many other positions, leading to unusual alternating backward and forward laminar flows of water.
Ke Wang, Yi Chen, Martin Wegener
wiley   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

Advanced Science, EarlyView.
An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu, Juan Qin, Si‐Yuan Wu, Xue‐Zhen Zhu, Yun‐Fei Cai, Pei‐Yao Sun, Hao Yang, Xing‐Yue Wang, Shu Li, Duo Wang, Hai‐Dong Zhu   +10 more
wiley   +1 more source

Peer Victimization and Non-Suicidal Self-Injury Among Chinese Adolescents: Moderating Roles of Teacher Emotional Support and Parent-Child Cohesion. [PDF]

Behav Sci (Basel)
Liu N, Li A, Xie Q, Yue M.
europepmc   +1 more source

Machine Learning Potential for Calcium Silicate Hydrates With Broad Compositional and Structural Diversity

Advanced Science, EarlyView.
Existing machine learning potentials remain limited in their ability to generalize across the broad chemical and structural variability of C–S–H. Here, a representative DFT‐labeled dataset is constructed through large‐scale model generation, redundancy‐controlled screening, first‐principles optimization, and targeted sampling of non‐equilibrium ...
Yunjian Li, Cheng Chen, Roland J.‐M. Pellenq, Zongjin Li, Jiaping Liu   +4 more
wiley   +1 more source

Toward relationship-based child welfare services

A relationship-based theoretical framework for child welfare services is proposed. Research literature is reviewed relative to attachment theory, relationship quality of maltreated child-parent and maltreated child-surrogate parent dyads, and effective ...
Goodman, Gail S., Lawler, Michael J., Shaver, Phillip R.   +2 more
core  

Intergenerational associations between parental low-carbon concern and early adolescents' low-carbon consumption behaviors: a moderated mediation model. [PDF]

Front Psychol
Li J, Fang Q, Zhang X.
europepmc   +1 more source

CHILD-PARENT RELATIONSHIPS IN REUNITED BIOLOGICAL FAMILY

SOCIETY AND SECURITY INSIGHTS, 2018
openaire   +2 more sources

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

Advanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong, Wenjun Zhou, Yuxiang Sun, Zihan Huang, Zhiyue Liu, Udhaya Kumar. S, Chenyan Li, Yi Lu, Chengchuang Song, Veronica C. Ciliberto, Makenna Mack, Lana E. Kim, Zhaoyong Hu, Fang Luo, Aihua Cao, Zheng Sun   +15 more
wiley   +1 more source

Longitudinal associations between relationship quality and prosocial behavior in Chinese adolescents: the mediating role of meaning in life. [PDF]

Front Psychiatry
Meng L, Li C, Dai T, Zhang S, Zhang B, Yang Q.   +5 more
europepmc   +1 more source