Results 151 to 160 of about 7,730,633 (395)

Representing the Child in Child Protective Proceedings: Toward A New Paradigm [PDF]

open access: yes, 2019
This article will attempt a new approach, one based on an analysis of the child\u27s interests in a child protective proceeding. As will be discussed in Part 1, most interests are surprisingly overlooked or barely articulated in the representation debate.
Sobie, Merril
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Aprendizagem contestada em ambiente de mudança radical

open access: yesRAE: Revista de Administração de Empresas, 2004
Este artigo oferece uma análise da aprendizagem nas organizações em condições de mudança radical, em que a reestruturação da organização foi motivada por uma mudança na ideologia e na propriedade. Discute-se que, nessas circunstâncias, a aprendizagem não
Suzana Braga Rodrigues   +2 more
doaj  

Work and family life balance [PDF]

open access: yes
Balancing paid work and family responsibilities is a major issue for employers, governments and families across the western world (OECD, 2002). In light of rapid changes in the roles and responsibilities of men and women, and in the organisation and ...
Centre for Community Child Health
core  

The effects of positive affective priming on Māori mothers' attributions for children's misbehaviours and appropriate methods of discipline : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University, Wellington, New Zealand [PDF]

open access: yes, 2009
This study is a test-retest experimental design which sets out to determine if Māori mothers, exposure to emotive (positive) photographs of Māori people (children interacting with adults) would influence their attributions and disciplinary responses for ...
Amor-Ponter, Vickie Walla
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Policy Brief - five years on [PDF]

open access: yes
It has been five years since the first edition of Policy Brief was launched (2006) with the strapline translating early childhood research evidence to inform policy and practice. The goal was to select important issues in child and family health, review
Centre for Community Child Health
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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