Results 161 to 170 of about 6,249,325 (354)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

CHILD HYGIENE [PDF]

American Journal of Public Health and the Nations Health, 1932
  +9 more sources

Factors Affecting the Dietary Lives in Mother-to-Child Households in Consideration of Mothers’ Childhood Experiences

, 2020
Osami MATSUDA, Akira Ishida, Akihiko Nishizawa   +2 more
openalex   +2 more sources

Semiparametric Multinomial Ordinal Model to Analyze Spatial Patterns of Child Birth Weight in Nigeria [PDF]

, 2016
Rasheed A. Adeyemi, Temesgen Zewotir, Shaun Ramroop   +2 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Parental perception of girl-child early marriage amongst the Urhobos in Nigeria

, 2018
Emmanuel A. Agege, Ezekiel Uba Nwose, Stella Odjimogho   +2 more
openalex   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Design of service delivery for a child obesity prevention and management program using technology convergence

, 2014
Ji‐Yun Hwang, Mi-Young Park, Kirang Kim, Sang Eun Lee, Jae Eun Shim   +4 more
openalex   +1 more source

ANALISIS PENEMPATAN TERSANGKA ANAK BERSAMA DENGAN ORANG DEWASA DALAM PERSPEKTIF PERLINDUNGAN HUKUM ANAK DI KEPOLISIAN RESORT PASER KALIMANTAN TIMUR [PDF]

The investigation process is an initial stage where a child is confronted by investigators or the police. The child suspect was placed in the same cell as the adult prisoner. This is clearly contrary to Law Number 11 of 2012 concerning the Child Criminal
Aprillianti, Riska
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source