Results 161 to 170 of about 7,730,633 (395)

Early childhood and the life course [PDF]

What happens to children in the early years has consequences right through the course of their lives. There are many opportunities to intervene and make a difference to the lives of children and young people.
Centre for Community Child Health
core  

Child Care [PDF]

, 1948
PDF pages ...
Pepoon, Lucile
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Infant Regulation: Associations with Child Language Development in a Longitudinal Cohort

, 2021
Fallon Cook, Laura Conway, Emina Omerovic, Petrea Cahir, Rebecca Giallo, Harriet Hiscock, Fiona Mensah, Lesley Bretherton, Edith L. Bavin, Patricia Eadie, Stephanie Brown, Sheena Reilly   +11 more
openalex   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Conservative management of unicystic ameloblastoma in a young child: Report of two cases

, 2011
Ritesh Kalaskar, AshokS Unawane, AshitaR Kalaskar, P.K. Pandilwar   +3 more
openalex   +1 more source

Resolution of refractory orbital cellulitis in an immunocompetent child: A case report

, 2021
Windi Eka Yulia Retnani, Mutmainah Mahyuddin, Sahar S.S. Alatas, Diajeng Ayesha Soeharto   +3 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Leveling the intra-household playing field: compensation and specialization in child labor allocation

, 2010
Ximena V. Del Carpio, Karen Macours
openalex   +2 more sources

Child self-report and parent ratings for the Strengths and Difficulties Questionnaire: Norms and agreement in a Swedish random population sample [PDF]

, 2017
Bojing Liu, Karin Engström, Isabel Jadbäck, Sara Ullman, Anne H. Berman   +4 more
openalex   +1 more source