Results 51 to 60 of about 495,655 (295)

Safeguarding children and young people from sexual exploitation (consultation document) [PDF]

open access: yes, 2010
"This guidance is designed to assist practitioners in preventing child sexual exploitation (CSE), protecting children and young people who are at risk of abuse or are abused through sexual exploitation, and disrupting and prosecuting those who perpetrate

core  

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu   +4 more
wiley   +1 more source

Updated trends in Child Maltreatment, 2012. [PDF]

open access: yes, 2013
National statistics from 2012 showed increases in some forms of child maltreatment for the first time in many years. While overall substantiated child maltreatment was flat from 2011 to 2012, there was a 2% rise in sexual abuse and a 5% rise in physical ...
Finkelhor, David   +3 more
core   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang   +7 more
wiley   +1 more source

Childhood Sexual Abuse [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2009
Sexual abuse is defined as use of child or adolescent by the adults for satisfying of sexual urges and needs with forcing, threatening or tricking. Sexual abuse can be in the form of sexual abuse without touch, sexual touch, interfemoral intercourse ...
Evrim Aktepe
doaj  

Multifaceted Glance on Childhood Sexual Abuse and Incest [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2018
An experience of domestic violence can lead to permanent physical, mental, and psychological harms, whether the child is a direct victim or a witness. Although having no standard definition, it is generally agreed that childhood sexual abuse and incest ...
Aslihan Okan Ibiloglu   +3 more
doaj   +1 more source

Which sexual abuse victims receive a forensic medical examination? : The impact of Children\u27s Advocacy Centers [PDF]

open access: yes, 2007
Objective This study examines the impact of Children\u27s Advocacy Centers (CAC) and other factors, such as the child\u27s age, alleged penetration, and injury on the use of forensic medical examinations as part of the response to reported child sexual ...
Cross, Theodore P   +4 more
core   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

open access: yesAdvanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi   +13 more
wiley   +1 more source

Investigation of Mothers' Childhood Trauma and Their Relationships with Their Children

open access: yesYüzüncü Yıl Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2023
This study aimed to examine mothers' childhood trauma situations and their relations with their children. A relational screening model was used in this research. The study group of the research consisted of 250 mothers.
Zeynep Nur Aydın Kılıç   +3 more
doaj   +1 more source

The Elimination of the Sexual Exploitation of Children: Two Policy Briefings [PDF]

open access: yes, 2012
The Oak Foundation child-abuse programme has funded and supported a range of civil society actors over the course of the last ten years, with the aim of reducing the incidence of the sexual exploitation of children, focusing primarily on work in East ...

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