Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by IKZF1 haploinsufficiency. Methods Peripheral immune cells from a patient with IKZF1 haploinsufficiency, patients with lupus with no currently known genetic mutations, and healthy controls were analyzed using single‐cell
Qi Zheng +6 more
wiley +1 more source
Implementing youth advisory boards with sexual minority adolescents and young men: sharing experiences, challenges and opportunities from East, South, and West Africa. [PDF]
Adebajo S +23 more
europepmc +1 more source
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola +14 more
wiley +1 more source
World Postpartum Haemorrhage Day: Renewing the Global Call to End Deaths From Postpartum Haemorrhage. [PDF]
PPH Roadmap Advocacy Working Group.
europepmc +1 more source
Body donor programs in Australia and New Zealand: Current status and future opportunities
Abstract Body donation is critical to anatomy study in Australia and New Zealand. Annually, more than 10,000 students, anatomists, researchers, and clinicians access tissue donated by local consented donors through university‐based body donation programs. However, little research has been published about their operations.
Rebekah A. Jenkin, Kevin A. Keay
wiley +1 more source
The challenges and opportunities for equitable global access to medications for paediatric rheumatology in low-to middle-income countries: a review on behalf of the Paediatric Global Task Force for Musculoskeletal Health. [PDF]
Scott C +12 more
europepmc +1 more source
Abstract Game‐based learning (GBL) is increasingly used in medical education to supplement traditional didactic learning methods. Adult learners in particular may benefit from GBL, given the autonomous and iterative nature of a well‐designed educational game.
Thomas J. Paddock, Erin P. Fillmore
wiley +1 more source
Opposing consensus science through scholarly practices: The role of claims maintenance
Abstract This study examines how three US‐based communities who oppose consensus science produce and disseminate scholarly‐like artifacts: pro‐life activists, Young Earth Creationists, and Anthropogenic Climate Crisis skeptics. Prior research shows that industry‐ or church‐backed advocacy campaigns often generate claims supported by these communities ...
Irene V. Pasquetto +3 more
wiley +1 more source
Establish Global Nutrition Research Strategies: The Meeting Report of the First SIOP Nutrition Research Forum. [PDF]
Gala RM +6 more
europepmc +1 more source
From disorientation to preparedness: Information practices as scaffolding in acute crises
Abstract This qualitative study examines how adults in Israel enacted information practices during an acute national crisis. Using the information transitions framework, we investigate how concrete practices emerge and evolve across three stages: understanding, negotiating, and resolving. Semi‐structured Zoom interviews with 18 adults were analyzed via
Lilach Alon +2 more
wiley +1 more source

