Enhancing Autism Spectrum Disorder Early Detection with the Parent-Child Dyads Block-Play Protocol and an Attention-enhanced GCN-xLSTM Hybrid Deep Learning Framework [PDF]
Autism Spectrum Disorder (ASD) is a rapidly growing neurodevelopmental disorder. Performing a timely intervention is crucial for the growth of young children with ASD, but traditional clinical screening methods lack objectivity. This study introduces an innovative approach to early detection of ASD. The contributions are threefold.
arxiv
Early BMI Change, Cognitive Decline, and CSF AD Biomarkers Alterations in Parkinson's Disease
ABSTRACT Objective To examine the relationship of early BMI change with subsequent cognitive decline, CSF AD biomarkers alterations, and progression to dementia in patients with PD. Methods Study data were prospectively collected from the PPMI cohort. Weight/height data at enrollment and second‐year clinical visit were utilized to calculate BMI change.
Rui Zhong, Kezhong Zhang
wiley +1 more source
Combination Therapy With Vigabatrin and Prednisolone Versus Vigabatrin Alone for Infantile Spasms
ABSTRACT Objective The study evaluated the effectiveness of combination therapy with vigabatrin and prednisolone versus vigabatrin alone for treating infantile epileptic spasms syndrome (IESS). Methods This single‐center, single‐blind, randomized trial enrolled infants aged 2–14 months with new‐onset IESS, randomly assigned them (1:1) to receive either
Rachata Boonkrongsak+6 more
wiley +1 more source
Controlled Comparison of Family Cognitive Behavioral Therapy and Psychoeducation/Relaxation Training for Child Obsessive-Compulsive Disorder [PDF]
John Piacentini+6 more
openalex +1 more source
Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study
ABSTRACT Objective Cerebral amyloid angiopathy (CAA) involves β‐amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R2) is a major source of contrast in MRI. This study tested the hypothesis that CAA is associated with R2, extracted the spatial pattern of CAA‐related R2 abnormalities, and evaluated ...
Md Tahmid Yasar+6 more
wiley +1 more source
The association between parent early adult drug use disorder and later observed parenting practices and child behavior problems: Testing alternate models. [PDF]
Jennifer A. Bailey+6 more
openalex +1 more source
Functional Limit Theorems for Hawkes Processes [PDF]
We prove that the long-run behavior of Hawkes processes is fully determined by the average number and the dispersion of child events. For subcritical processes we provide FLLNs and FCLTs under minimal conditions on the kernel of the process with the precise form of the limit theorems depending strongly on the dispersion of child events.
arxiv +1 more source
Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with limited treatment options. Transcranial direct current stimulation (tDCS) shows promise as a neuromodulatory intervention in various neurological disorders, but its application in ALS, particularly in a remote, home‐based format, remains underexplored.
Sangeetha Madhavan+6 more
wiley +1 more source
Ihmeelliset vuodet ohjelma perheiden tukena lasten käytöshäiriöissä : Kirjallisuuskatsaus [PDF]
Opinnäytetyö liittyy Omaiset mielenterveystyön tukena, Uudenmaan yhdistys ry:n projektiin Ihmeelliset vuodet vanhemmuusohjelma. Ihmeelliset vuodet ohjelma on lasten käytöshäiriöiden hoito- ja preventio ohjelma.
Rantakokko, Janita, Pulkkinen, Tanja
core
HPDL Variant Type Correlates With Clinical Disease Onset and Severity
ABSTRACT Objective Recently, a mitochondrial encephalopathy due to biallelic HPDL variants was described, associated with a broad range of clinical manifestations ranging from severe, infantile‐onset neurodegeneration to adolescence‐onset hereditary spastic paraplegia. HPDL converts 4‐hydroxyphenylpyruvate acid (4‐HPPA) into 4‐hydroxymandelate (4‐HMA),
Eun Hye Lee+19 more
wiley +1 more source