Results 81 to 90 of about 1,182,149 (391)

Parenting Preschoolers with Disruptive Behavior Disorders: Does Child Gender Matter? [PDF]

, 2013
Parental responses to child behavior can have an important impact on later behavioral outcomes. Children with Disruptive Behavior Disorders often engage in externalizing and disruptive behaviors, which usually elicit negative responses from parents. Boys
Gonzalez, Antonya M
core   +1 more source

Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption

Molecular Oncology, Volume 19, Issue 4, Page 1203-1228, April 2025.
MiR‐99a‐5p/miR‐100‐5p (functionally identical) and miR‐125b‐5p microRNAs are downregulated in malignant germ cell tumors (GCTs). Combination replenishment of these microRNAs using mimics resulted in growth inhibition in representative cell lines, with consequent downregulation of target genes involved in cell cycle (confirmed by flow cytometry) and ...
Marta Ferraresso, Shivani Bailey, Luz Alonso‐Crisostomo, Dawn Ward, Christos Panayi, Zachary G. L. Scurlock, Harpreet K. Saini, Stephen P. Smith, James C. Nicholson, Anton J. Enright, Cinzia G. Scarpini, Nicholas Coleman, Matthew J. Murray   +12 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

KLEPTOMANIA AND ATTENTION DEFICIT HYPERACTIVITY DISORDER- CASE REPORT

Sanamed, 2018
Kleptomania as a type of impulse control disorder (ICD) characterized by an inability to resist urges to steal objects not valuable or needed for personal use.
Ayyildiz Didem
doaj   +1 more source

The relations of metabolic syndrome to anxiety and depression symptoms in children and adults [PDF]

, 2017
Metabolic syndrome is a cluster of five factors (elevated systolic blood pressure, elevated blood glucose, elevated triglycerides, large waist circumference, and decreased HDL) that are related to a greater chance of heart disease, stroke, and diabetes ...
Michael, Jennifer R
core   +1 more source

A portable audio/video recorder for longitudinal study of child development [PDF]

, 2012
Collection and analysis of ultra-dense, longitudinal observational data of child behavior in natural, ecologically valid, non-laboratory settings holds significant promise for advancing the understanding of child development and developmental disorders ...
Goodwin, Matthew, Roy, Deb K., Vosoughi, Soroush, Washabaugh, Bill   +3 more
core   +3 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Efficacy of the Social Information Processing Model in Predicting Behavioral Disorders

Caspian Journal of Neurological Sciences, 2017
Background: The social information processing model is one of the most up-to-date cognitive models in the field of interpersonal interactions. This social-interaction-based model can be successfully used to investigate the reasons for emotional and ...
Abdolhossein Shamsi, Ahmad Abedi, Amir Ghamarani, Ahmad Yarmohamadian   +3 more
doaj  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Behavioral characteristics of dysphonic children: integrative literature review

CoDAS
PURPOSE: Integrative review of the scientific literature about the behavioral characteristics of dysphonic children discussing profiled and their etiologic relationship with the voice disorder, seeking to define recommendations on the importance of ...
Andréa Alves Maia, Ana Cristina Côrtes Gama, Arthur Melo e Kümmer   +2 more
doaj   +1 more source