Results 41 to 50 of about 3,099,799 (302)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Gaps in the Child Tuberculosis Care Cascade in 32 Rural Communities in Uganda and Kenya. [PDF]

, 2017
Background:Reducing tuberculosis (TB) deaths among children requires a better understanding of the gaps in the care cascade from TB diagnosis to treatment completion.
Ayieko, James, Bukusi, Elizabeth A, Chamie, Gabriel, Charlebois, Edwin D, Clark, Tamara D, Cohen, Craig R, Havlir, Diane V, Kamya, Moses R, Kwarisiima, Dalsone, Marquez, Carina, Mwangwa, Florence, Owaraganise, Asiphas, Petersen, Maya, Plenty, Albert, Ruel, Theodore D, Tram, Khai Hoan   +15 more
core   +2 more sources

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Novel PIP5K1C variant identified in a Chinese pedigree with lethal congenital contractural syndrome 3

BMC Pediatrics
Background Biallelic pathogenic variants in PIP5K1C (MIM #606,102) lead to lethal congenital contractural syndrome 3 (LCCS3, MIM #611,369), a rare autosomal recessive genetic disorder characterized by small gestational age, severe multiple joint ...
Fang Zhang, Hongmei Guo, Xinlong Zhou, Zhengxi Deng, Qiuhong Xu, Qingming Wang, Haiming Yuan, Jianhua Luo   +7 more
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Malnutrition and related factors among syphilis-exposed uninfected infants and young children in Hunan province from 2018 to 2020

Zhongguo gonggong weisheng
ObjectiveTo investigate the prevalence of malnutrition among syphilis-exposed uninfected (SEU) infants and young children in Hunan province and explore its related factors.
Huixia LI, Juan XIAO, Danfeng TAN, Shan YUAN, Guangwen HUANG, Ying TU, Min YANG, Jie GAO   +7 more
doaj   +1 more source

The Effect of FOXC2-AS1 on White Adipocyte Browning and the Possible Regulatory Mechanism

Frontiers in Endocrinology, 2020
Obesity has become a worldwide epidemic, and obesity-related problems are becoming more severe in public health. Increasing brown adipose tissue (BAT) mass or/and activity in mice and humans has been demonstrated to help lose weight and improve whole ...
Yan Wang, Siyu Hua, Siyu Hua, Xianwei Cui, Yan Cao, Juan Wen, Juan Wen, Xia Chi, Xia Chi, Chenbo Ji, Chenbo Ji, LingXia Pang, LingXia Pang, Lianghui You, Lianghui You   +14 more
doaj   +1 more source

2017 Report on Child Care in Cook County [PDF]

, 2017
The year ending June 30, 2016 saw several significant shocks occur to child care services in Cook County. An unprecedented restriction of eligibility in the Illinois Child Care Assistance Program (CCAP) imposed a period of great uncertainty on parents ...

core  

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source