Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Assessment of Children with Language Developmental Delay: Korean Infant and Child Development Test (KICDT) and Preschool Receptive-Expressive Language Scale (PRES), Sequenced Language Scale for Infant (SELSI) [PDF]
, 2015 최석원 +5 more
openalex +1 more source
Child labor, education, and children's rights [PDF]
Child labor is widespread, and bad for development, both that of the individual child, and of the society and economy in which she, or he lives. If allowed to persist to the current extent,child labor will prevent the achievement of the Millennium ...
Betcherman, Gordon +3 more
core
Resources for Workplace Flexibility, Families and Child Development [PDF]
, 2011 A list of resources for Workplace Flexibility, Families and Child ...
Workplace Flexibility 2010, Georgetown University Law Center
core +1 more source
INF2‐Related Charcot–Marie–Tooth Disease in a Japanese Cohort: Genetic and Clinical Insights
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background INF2 mutations cause focal segmental glomerulosclerosis (FSGS) and Charcot–Marie–Tooth disease (CMT). Accurate genetic diagnosis is critical, as INF2‐related FSGS is typically resistant to immunotherapy yet rarely recurs after transplantation, and its associated neuropathy can mimic treatable immune‐mediated disorders such as ...
Chikashi Yano +27 more
wiley +1 more source
Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco +18 more
wiley +1 more source
Cooperative Child Care for Rural Residents: The Experience from California [PDF]
Over the past third of a century, Western welfare states have made policy shifts toward decentralization and privatization, and expected the private non-profit sector to take a larger role in addressing social welfare needs.
Coontz, Elizabeth Kim, Esper, Elizabeth
core +1 more source
Treatment Outcomes for At-Risk Young Children With Behavior Problems: Toward a New Definition of Success [PDF]
, 2014 This study examined the outcomes of Early Pathways (EP), an in-home parent–child therapy program with 447 at-risk children younger than 5 years of age who were referred for severe behavior and emotional problems, such as aggression, oppositional behavior,
Fox, Robert A. +2 more
core +1 more source
CHILD SURVIVAL AND CHILD DEVELOPMENT IN DEVELOPING COUNTRIES [PDF]
Journal of Paediatrics and Child Health, 2011 openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann +6 more
wiley +1 more source