Results 131 to 140 of about 3,390,395 (296)

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

FEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash, Campbell W. Gourlay, Ina Oehme, Michelle D. Garrett, Jindrich Cinatl Jr, Mark N. Wass, Martin Michaelis   +6 more
wiley   +1 more source

Implementation of a parent training intervention (SPARCK) to prevent childhood mental health problems: study protocol for a pragmatic implementation trial in Norwegian municipalities

Trials
Background Effective evidence-based interventions (EBI) are necessary to prevent and avoid negative life trajectories for children with mental health problems.
Anette Arnesen Grønlie, Agathe Backer-Grøndahl, Ragnhild Bang Nes, Maria Begoña Gomez, Truls Tømmerås   +4 more
doaj   +1 more source

Early detection of students’ mental health issues from a traditional daily health observation scheme in Japanese schools and its digitalization

Frontiers in Public Health
ObjectiveThe implementation of school-based mental health screening offers promise for early detection of mental health issues in children; however, various barriers hinder its widespread adoption.
Tomoko Nishimura, Tomoko Nishimura, Tomoko Nishimura, Manabu Wakuta, Manabu Wakuta, Yuko Osuka, Yuko Osuka, Nobuaki Tsukui, Nobuaki Tsukui, Nobuaki Tsukui, Ikue Hirata, Ikue Hirata, Michio Takahashi, Michio Takahashi, Masaki Adachi, Masaki Adachi, Taiichi Katayama, Taiichi Katayama, Kyoko Aizaki, Kyoko Aizaki, Motofumi Sumiya, Motofumi Sumiya, Sayaka Kawakami, Sayaka Kawakami, Toshiki Iwabuchi, Toshiki Iwabuchi, Atsushi Senju, Atsushi Senju   +27 more
doaj   +1 more source

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source

The relationship between social anxiety levels and effective communication skills of adolescents participating in sports

Scientific Reports
The present study examines the relationship between social anxiety levels and effective communication skills in adolescents engaged in sports. The correlational study was conducted with 352 voluntary adolescents aged 15 to 18 enrolled in a sports high ...
Alev Üstündağ, Semanur Haydaroğlu, Dilara Sayan, Merve Güngör   +3 more
doaj   +1 more source

Multifaceted perception of school climate: association between students’ and teachers’ perceptions and other teacher factors

Frontiers in Education
IntroductionThis study aimed to investigate whether there is a significant association between teachers’ and students’ perceptions of school climate, and if not, whether teacher factors are associated with the respective perceptions.MethodsThe ...
Ikue Hirata, Ikue Hirata, Tomoko Nishimura, Tomoko Nishimura, Tomoko Nishimura, Yuko Osuka, Yuko Osuka, Manabu Wakuta, Manabu Wakuta, Nobuaki Tsukui, Nobuaki Tsukui, Nobuaki Tsukui, Kenji J. Tsuchiya, Kenji J. Tsuchiya, Atsushi Senju, Atsushi Senju   +15 more
doaj   +1 more source

Developmental Diagnosis. Normal and Abnormal Child Development

, 1948

openalex   +1 more source

The Development of the Infant and Young Child: Normal and Abnormal [PDF]

, 1966
Ronald S. Illingworth
openalex   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Retinal hemorrhages and damages from tractional forces associated with infantile abusive head trauma evaluated by wide-field fundus photography

Scientific Reports
We evaluated the distribution and types of retinal hemorrhages (RHs) and other damages in eyes with abusive head trauma (AHT). This retrospective, consecutive case series of AHT and non-AHT conditions involved 54 children with AHT, 43 children with head ...
Noriyuki Azuma, Tomoyo Yoshida, Tadashi Yokoi, Sachiko Nishina, Satoko Uematsu, Mikiko Miyasaka   +5 more
doaj   +1 more source