Results 41 to 50 of about 974,916 (295)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

The Study of Child Development Norms of Thai Children Age from Birth to 5 Years using Child Development Assessment Tools Developed by the Mental Health Department, Ministry of Public Health, Thailand

International Journal of Child Development and Mental Health, 2013
This study aims to determine the development norms of Thai children age from birth to 5 years and to compare the assessment items of a child development assessment tool for children age from birth to 5 years, developed by the Department of Mental Health,
Samai Sirithongthaworn, Atsawin Narkpongphun, Nonglak Pongtaweeboon, Pinyo Itsarapong, Wasana Kasemsuk, Suleelak Pila, Preechaya Phrommin, Saowalak Langaphin, Usanee Sutthibuta, Kittiporn Thanu   +9 more
doaj  

Consensus on the Establishment and Operational Standards of Standardized Growth-and-Development Medical Centers Based on Active Health Principles (2025)

Xiehe Yixue Zazhi
With accelerated socioeconomic development and structural lifestyle changes, childhood and adolescent growth and developmental disorders in China have exhibited increasing complexity and a trend toward earlier onset, while the incidence of certain ...
China Behavioral Medical Research Center for Growth and Development, Behavioral Medicine Branch of Chinese Medical Association, Committee on Growth, Development and Metabolism, China Maternal and Child Health Research Association   +1 more
doaj   +1 more source

Elevated risk of attention deficit hyperactivity disorder (ADHD) in Japanese children with higher genetic susceptibility to ADHD with a birth weight under 2000 g

BMC Medicine, 2021
Background Both genetic and pre- and perinatal factors, including birth weight, have been implicated in the onset of attention deficit hyperactivity disorder (ADHD) traits among children.
Md Shafiur Rahman, Nagahide Takahashi, Toshiki Iwabuchi, Tomoko Nishimura, Taeko Harada, Akemi Okumura, Nori Takei, Yoko Nomura, Kenji J. Tsuchiya   +8 more
doaj   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

A Study of Child Developmental Norms for Children from birth to 5 years of age in Chiang Mai

International Journal of Child Development and Mental Health, 2013
This study aims to determine the developmental norms for children from birth to 5 years of age who live in Chiang Mai and to identify an order of assessment items of a child development tool for children from birth to 5 years of age, of the Department of
Samai Sirithongthaworn, Atsawin Narkpongphun, Nonglak Pongtaweeboon, Pinyo Itsarapong, Wasana Kasemsuk, Suleelak Pila, Preechaya Phrommin, Saowalak Langaphin, Usanee Sutthibuta, Kittiporn Thanu   +9 more
doaj  

Exploring Lifestyles and Sensory Processing Patterns of Toddlers in Relation to Sleep Patterns Using Body Movement Analysis

Clocks & Sleep
This study explored the impact of lifestyle habits and sensory processing patterns on sleep quality by analyzing body movements (BMs) during the first and last 3 h of sleep in toddlers. We collected cross-sectional data about sleep-related habits from 58
Azusa Ono, Yoshiko Iwatani, Arika Yoshizaki, Tomoko Nishimura, Ikuko Mohri, Kuriko Kagitani-Shimono, Masako Taniike   +6 more
doaj   +1 more source

Longitudinal impact of COVID-19 pandemic on mental health of children in the ABCD study cohort

Scientific Reports, 2022
A large longitudinal study on the impact of the COVID-19 pandemic on mental health in children is limited. This large-scale longitudinal observational study examines the pandemic’s effects on children’s mental health while considering the effects of ...
Sayo Hamatani, Daiki Hiraoka, Kai Makita, Akemi Tomoda, Yoshifumi Mizuno   +4 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Journal club: Integrating research awareness into postgraduate nurse training

Curationis, 2014
Background: Evidence-based nursing requires nurses to maintain an awareness of recently published research findings to integrate into their clinical practice.
Clare Davis, Inger Hendry, Hilary Barlow, Angela Leonard, Lee-Ann White, Minette Coetzee   +5 more
doaj   +1 more source