Results 51 to 60 of about 18,495,960 (408)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Elevated risk of attention deficit hyperactivity disorder (ADHD) in Japanese children with higher genetic susceptibility to ADHD with a birth weight under 2000 g

BMC Medicine, 2021
Background Both genetic and pre- and perinatal factors, including birth weight, have been implicated in the onset of attention deficit hyperactivity disorder (ADHD) traits among children.
Md Shafiur Rahman, Nagahide Takahashi, Toshiki Iwabuchi, Tomoko Nishimura, Taeko Harada, Akemi Okumura, Nori Takei, Yoko Nomura, Kenji J. Tsuchiya   +8 more
doaj   +1 more source

Designing Parent-child-robot Interactions to Facilitate In-Home Parental Math Talk with Young Children [PDF]

arXiv, 2023
Parent-child interaction is critical for child development, yet parents may need guidance in some aspects of their engagement with their children. Current research on educational math robots focuses on child-robot interactions but falls short of including the parents and integrating the critical role they play in children's learning.
arxiv  

NORMAL DEVELOPMENT OF THE CHILD [PDF]

AJN, American Journal of Nursing, 1922
n ...
openaire   +2 more sources

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Study protocol for a randomized controlled trial of supportive parents – coping kids (SPARCK)—a transdiagnostic and personalized parent training intervention to prevent childhood mental health problems

BMC Psychology
Background To meet the scientific and political call for effective prevention of child and youth mental health problems and associated long-term consequences, we have co-created, tested, and optimized a transdiagnostic preventive parent-training ...
T. Tømmerås, A. Backer-Grøndahl, A. Høstmælingen, H. Laland, M. B. Gomez, A. Apeland, L. R. A. Karlsson, A. A. Grønlie, S. Torsvik, G. E. Bringedal, Advisory Consortium, Aas Monica, Phillip Andrew Fisher, Frances Gardner, John Kjøbli, Ira Malmberg-Heimonen, Helene Amundsen Nissen-Lie   +16 more
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Salivary oxytocin concentrations in seven boys with autism spectrum disorder received massage from their mothers: a pilot study

Frontiers in Psychiatry, 2015
Seven male children with autism spectrum disorder (ASD), aged 8 – 12 years, attending special education classrooms for ASD and disabled children, were assigned to receive touch therapy. Their mothers were instructed to provide gentle touch in the massage
Shuji eTsuji, Teruko eYuhi, Kazumi eFuruhara, Shogo eOhta, Yuto eShimizu, Haruhiro eHigashida   +5 more
doaj   +1 more source

Poverty and Child Development [PDF]

Developmental Medicine & Child Neurology, 1968
SUMMARYThe effects of poverty on child development are looked at by reference to other social indices, such as the statistical returns of the Registrar General. These effects begin before birth with higher rates among the poor of still‐birth, abortion, prematurity, perinatal mortality and the risk of congenital malformations.
Gillian Yudkin, Simon Yudkin
openaire   +3 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source