Results 91 to 100 of about 159,153 (291)

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

open access: yesAdvanced Science, EarlyView.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu   +7 more
wiley   +1 more source

Sleep physiology and sleep disorders in childhood

open access: yesNature and Science of Sleep, 2011
Hanan M El ShakankiryKing Fahd University Hospital, Al Dammam University, Al Khobar, Kingdom of Saudi ArabiaAbstract: Sleep has long been considered as a passive phenomenon, but it is now clear that it is a period of intense brain activity involving ...
El Shakankiry HM
doaj  

Healing Generational Trauma in Aboriginal Canadians

open access: yesVoices in Bioethics, 2018
Case Introduction: Makayla’s story On January 19, 2015, Makayla Sault, an 11 year old Aboriginal girl, died of leukemia [1].  Although her physicians gave her a 75% cure rate with treatment, she and her family refused chemotherapy in favor of pursuing
Jocelyn Chase
doaj   +1 more source

Sulfated Cyclocarya Paliurus Polysaccharide Sorchestrates the Gut Microbiome to Mobilize a Host‐Derived 12‐HEPE Against Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen   +11 more
wiley   +1 more source

Vitamin D3 levels in children with autism spectrum disorders

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: In this study, it is aimed to define serum levels of vitamin D3, calcium (Ca), phosphorus (P), alkaline phosphatase (ALP) and folate in young children with Autism Spectrum Disorders (ASD), to compare them with those of normal controls and to ...
Cagatay Ugur, Cihat Kagan Gurkan
doaj  

Pediatric Developmental Screening: Understanding and Selecting Screening Instruments [PDF]

open access: yes, 2008
Based on a review of research on developmental screening instruments, provides a manual for selecting and applying tools for screening for both general and specific problems.
Dennis Drotar   +2 more
core  

Developmental motor profile in preschool children with primary stereotypic movement disorder [PDF]

open access: yes, 2019
Aim. Different neuropsychological dysfunctions have been described in children with primary Stereotypic Movement Disorder (SMD), mainly attention or motor coordination problems.
Baglioni, Valentina   +6 more
core   +1 more source

Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction

open access: yesAdvanced Science, EarlyView.
This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng   +12 more
wiley   +1 more source

Assessment of Metabolic Parameters For Autism Spectrum Disorders [PDF]

open access: yes, 2009
Autism is a brain development disorder that first appears during infancy or childhood, and generally follows a steady course without remission. Impairments result from maturation-related changes in various systems of the brain.
Ghosh, S   +4 more
core  

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

open access: yesAdvanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai   +7 more
wiley   +1 more source

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