ChemistryOpen, EarlyView.Molecular dynamics analysis of novel statin analogs shows that binding induces superior stabilization of HMG‐CoA reductase. As shown by the solvent‐accessible surface area profile, ligand‐induced rigidity offers a new, effective strategy for drug design. Cardiovascular diseases remain a leading cause of global mortality.
Yoshua B. Mtulo +4 more
wiley +1 more source
Quality of life in a family-centric applied behavior analysis model: A case series study. [PDF]
PLoS OneCiobanu M +7 more
europepmc +1 more source
How can children and young people have a voice in urban treescapes?
People and Nature, EarlyView.Abstract Scientific understanding of climate change has, to date, failed to result in sufficient action. This paper proposes that a deficit model of top‐down learning and dissemination in relation to public engagement with science may be part of the problem, particularly when considering the attitudes, values and empowerment of children and young ...
Simon Carr +10 more
wiley +1 more source
Linking ADHD to Depression in Adolescents: the Mediating Role of Social Skills. [PDF]
Res Child Adolesc PsychopatholLoomis AM +3 more
europepmc +1 more source
Pediatric Investigation, EarlyView.The Paradigm Shift Program, a comprehensive training program for parents of neurodivergent children with pathological demand avoidance (PDA), was feasible and acceptable, and there were significant improvements in parents’ well‐being following program completion.
Noelle E. Carlozzi +6 more
wiley +1 more source
The Autism Open Clinical Model (A.-O.C.M.) as a Phenomenological Framework for Prompt Design in Parent Training for Autism: Integrating Embodied Cognition and Artificial Intelligence. [PDF]
Brain SciMorfini F, Cesarano SGD.
europepmc +1 more source
Journal of Field Robotics, EarlyView.ABSTRACT Personal autonomous vehicles can sense their surrounding environment, plan their route, and drive with little or no involvement of human drivers. Despite the latest technological advancements and the hopeful announcements made by leading entrepreneurs, to date no personal vehicle is approved for road circulation in a “fully” or “semi ...
Xingshuai Dong +13 more
wiley +1 more source
Mental health-related sickness absences in parents of children with mental disorders or neurodevelopmental conditions. [PDF]
Epidemiol Psychiatr SciGutvilig M +5 more
europepmc +1 more source
Integrating multimodal data and machine learning for entrepreneurship research
Strategic Entrepreneurship Journal, EarlyView.Abstract Research Summary Extant research in neuroscience suggests that human perception is multimodal in nature—we model the world integrating diverse data sources such as sound, images, taste, and smell. Working in a dynamic environment, entrepreneurs are expected to draw on multimodal inputs in their decision making.
Yash Raj Shrestha, Vivianna Fang He
wiley +1 more source
Referral Patterns, Pathways to Care, Symptom Profile, and Diagnoses of Children Attending a Child Psychiatry Unit in South India: A Retrospective Chart Review. [PDF]
Indian J Psychol MedVishwanath R +3 more
europepmc +1 more source