Results 31 to 40 of about 80,894 (249)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

SOCIAL AND ENVIRONMENTAL PROBLEMS ASSOCIATED WITH CHILD LABOUR [PDF]

open access: yesJournal of Environmental Science
The current study aims to identify the social and environmental problems associated with child labour, in addition to determinining the nature of the relationship between child labour and the decline of their right to develop their abilities and skills ...
Doaa M. El Sayed   +2 more
doaj   +1 more source

Thinking and labour (reading Vygotsky)

open access: yesКультурно-историческая психология, 2023
Lev Vygotsky connected the development of “higher forms of thinking” with labour, and claimed that this connection is “central and basic”, allowing to unfold the peculiarities of children’s thinking and the new in
A.D. Maidansky
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Comment: The New ILO-Report on Child Labour – a Document of Self-Satisfaction

open access: yesSocial Work and Society, 2006
The Second Global Report on Child Labour presented by the International Labour Office (ILO) in May 2006 is titled: “The End of Child Labour: Within Reach”.
Philip Meade
doaj   +2 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Suppression of child labour: Brief overview of international standards [PDF]

open access: yesStrani pravni život, 2018
The notion of child labour is well determined by relevant international instruments and it can be said that it is theoretically unquestionable. In practice, however, there are various concerns about how to distinguish legal child work from illegal child ...
Reljanović Mario
doaj  

Health consequences of child labour in Bangladesh

open access: yesDemographic Research, 2014
Background: The paper examines the effect of child labour on child health outcomes in Bangladesh, advancing the methodologies and the results of papers published in different journals.
Salma Ahmed, Ranjan Ray
doaj   +1 more source

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