Results 121 to 130 of about 965,870 (302)

Hunger and Famine in The Horn of Africa: A Vulnerability Approach

İmgelem
The lack of precipitation in the 2020-2022 rainy season has resulted in a food crisis in the Horn of Africa. Attributing the famine exclusively to rising global temperatures, climate change, prolonged dry periods, or flooding overlooks the underlying ...
Erdal Bayar
doaj   +1 more source

3D‐Printed Dynamic Heart Model With Left‐Side Anatomy and Integrated Sensor for Edge‐to‐Edge Repair and Regurgitation Reduction

Advanced Materials Technologies, EarlyView.
This work presents a fully synthetic, 3D‐printed dynamic heart model with left‐side anatomy featuring sutured mitral valve chordae tendineae analogs, embedded actuators for physiologic wall contraction, and customized flexible pressure sensors for the left ventricle.
Alejandro Guillen Obando, Hongyi Shen, Myles McGovern, Yusen Zhang, Vivien Lin, Darryl Fu, Ryan Baumwart, Kaiyan Qiu   +7 more
wiley   +1 more source

Poverty, Undernutrition, and Child Mortality: Some Inter-Regional Puzzles and their Implications for Research and Policy [PDF]

This paper examines the relationship between measures of income poverty, undernourishment, childhood undernutrition, and child mortality in developing countries.
Klasen, Stephan
core   +3 more sources

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Large language models and child mortality: opportunities and challenges in answering public queries on under-5 causes

Frontiers in Public Health
BackgroundReducing under-5 mortality remains a global health priority. Large language models (LLMs) are increasingly used by the public to access medical information.
Yi Yang, Yi Yang, Yi Yang, Tingxi Zhu, Tingxi Zhu, Hongju Chen, Hongju Chen, Yao Zhang, Yao Zhang, Chao Zhang, Dengjun Liu, Dengjun Liu, Yanxia Mao, Yanxia Mao, Jiaxi Wu, Jiaxi Wu, Tao Xiong, Tao Xiong, Tao Xiong   +18 more
doaj   +1 more source

Understanding the Effects of Sibling Composition on Child [PDF]

This paper argues that spacing between consecutive births is an important aspect of competition among siblings for survival. Since parents simultaneously choose their desired values of birth spacing and the amount of time and other resources invested in ...
Gerald Makepeace, Sarmistha Pal
core  

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Child Mortality Reacts to Relative Prices [PDF]

This paper argues that, for a given average level of income per capita, the real currency depreciation has a negative impact on child survival, due to higher relative prices of tradable goods such as food and drug. This assumption is significantly tested
Christopher GRIGORIOU, Patrick GUILLAUMONT   +1 more
core  

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Gender Patterns in Vietnam's Child Mortality [PDF]

We analyze child mortality in Vietnam focusing on gender aspects. Contrary to several other countries in the region, mortality rates for boys are substantially larger than for girls.
Koning, Ruud H., Kooreman, Peter, Pham, Thong Le, Wiersma, Doede   +3 more
core